Bharat Anchit, Jain Nikita, Singh Veerpal
Indiana University Health Ball Memorial Hospital, Muncie, IN, USA.
Chicago Medical School, Rosalind Franklin University of Medicine and Sciences, Mchenry, IL, USA.
J Med Cases. 2020 Jun;11(6):174-177. doi: 10.14740/jmc3488. Epub 2020 May 28.
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has ravaged the global society as we know it. As almost a dozen pharmaceutical agents go into randomized controlled clinical trials, multiple studies have surfaced trying to associate a hypercoagulable state to coronavirus disease 2019 (COVID-19) patients. We report two COVID-19 cases who presented with occlusive pulmonary embolism (PE) strongly supporting a hypercoagulable state incurred by SARS-CoV-2. This is significant as it is one of the early reports of such an initial presentation of COVID-19 in the USA. Through our report, we invite the medical community to share a perspective about long-term management guidelines for SARS-CoV-2 associated venous thromboembolism (VTE) and prompt future research.
严重急性呼吸综合征冠状病毒2(SARS-CoV-2)已经肆虐了我们所知的全球社会。随着近十二种药物进入随机对照临床试验,多项研究浮出水面,试图将高凝状态与2019冠状病毒病(COVID-19)患者联系起来。我们报告了两例表现为闭塞性肺栓塞(PE)的COVID-19病例,有力地支持了SARS-CoV-2引起的高凝状态。这很重要,因为这是美国关于COVID-19这种初始表现的早期报告之一。通过我们的报告,我们邀请医学界就SARS-CoV-2相关静脉血栓栓塞(VTE)的长期管理指南分享观点,并推动未来的研究。