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与新型冠状病毒肺炎感染相关的迟发性脑病

Late-Onset Encephalopathy Associated With SARS-CoV-2 Infection.

作者信息

Reming Katie, Sivakumar Keithan, Moheb Negar, Nizam Ahmad, Yacoub Hussam A

机构信息

Morsani College of Medicine, University of South Florida, Tampa, FL, USA.

Department of Neurology, Lehigh Valley Health Network, Allentown, PA, USA.

出版信息

J Neurol Res. 2020 Dec;10(6):237-239. doi: 10.14740/jnr614. Epub 2020 Dec 9.

Abstract

Several typical and atypical neurological manifestations of viral pandemics have been reported. Neurological manifestations of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have recently been reported. In this case report, we present a patient with encephalopathy as a late neurologic manifestation of SARS-CoV-2 infection. The patient initially tested positive for the novel coronavirus after presenting with fever, cough, and altered mental status. The symptoms resolved within 5 - 7 days and the patient was discharged home. He subsequently developed worsening encephalopathy in the absence of respiratory symptoms, required hospitalization, and tested positive for SARS-CoV-2. Complete workup was unrevealing otherwise. We advise clinicians to be aware of late neurological manifestations of coronavirus disease 2019 (COVID-19) including encephalopathy.

摘要

已有关于病毒性大流行的几种典型和非典型神经表现的报道。最近有关于严重急性呼吸综合征冠状病毒2(SARS-CoV-2)神经表现的报道。在本病例报告中,我们介绍了一名患有脑病的患者,这是SARS-CoV-2感染的晚期神经表现。该患者最初在出现发热、咳嗽和精神状态改变后新型冠状病毒检测呈阳性。症状在5至7天内缓解,患者出院回家。随后,他在没有呼吸道症状的情况下出现了脑病加重,需要住院治疗,且SARS-CoV-2检测呈阳性。其他全面检查未发现异常。我们建议临床医生注意2019冠状病毒病(COVID-19)的晚期神经表现,包括脑病。

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