• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

相似文献

1
Converging evidence for inhibition of transcriptional control in high-grade gliomas.高级别胶质瘤中抑制转录调控的汇聚证据。
Neuro Oncol. 2021 Aug 2;23(8):1225-1227. doi: 10.1093/neuonc/noab112.
2
Deregulated expression of the clock genes in gliomas.时钟基因在神经胶质瘤中的失调表达。
Technol Cancer Res Treat. 2013 Feb;12(1):91-7. doi: 10.7785/tcrt.2012.500250.
3
Genetic and clinical characterization of B7-H3 (CD276) expression and epigenetic regulation in diffuse brain glioma.弥漫性脑胶质瘤中 B7-H3（CD276）表达的遗传和临床特征及表观遗传调控
Cancer Sci. 2018 Sep;109(9):2697-2705. doi: 10.1111/cas.13744. Epub 2018 Aug 29.
4
Deregulated expression of the Per1 and Per2 in human gliomas.人类神经胶质瘤中 Per1 和 Per2 的表达失调。
Can J Neurol Sci. 2010 May;37(3):365-70. doi: 10.1017/s031716710001026x.
5
IDH1 status is significantly different between high-grade thalamic and superficial gliomas.异柠檬酸脱氢酶1（IDH1）状态在高级别丘脑胶质瘤和浅表性胶质瘤之间存在显著差异。
Cancer Biomark. 2017 Aug 23;20(2):183-189. doi: 10.3233/CBM-170175.
6
Signal transduction molecules in gliomas of all grades.各级别胶质瘤中的信号转导分子。
J Neurooncol. 2009 Jan;91(1):19-26. doi: 10.1007/s11060-008-9683-5. Epub 2008 Sep 1.
7
Correlation between chromosome 1p/19q status and VEGF mRNA expression in gliomas.胶质瘤中1号染色体短臂/19号染色体长臂状态与血管内皮生长因子信使核糖核酸表达的相关性
Genet Mol Res. 2016 Jan 26;15(1):gmr7322. doi: 10.4238/gmr.15017322.
8
Topographic correlates of driver mutations and endogenous gene expression in pediatric diffuse midline gliomas and hemispheric high-grade gliomas.儿童弥漫性中线胶质瘤和半球性高级别胶质瘤中驱动突变和内源性基因表达的地形相关性。
Sci Rep. 2021 Jul 13;11(1):14377. doi: 10.1038/s41598-021-92943-0.
9
Deregulated expression of cry1 and cry2 in human gliomas.cry1和cry2在人类胶质瘤中的表达失调。
Asian Pac J Cancer Prev. 2012;13(11):5725-8. doi: 10.7314/apjcp.2012.13.11.5725.
10
Loss of 5'-Methylthioadenosine Phosphorylase (MTAP) is Frequent in High-Grade Gliomas; Nevertheless, it is Not Associated with Higher Tumor Aggressiveness.5'-甲基硫腺苷磷酸化酶（MTAP）缺失在高级别胶质瘤中很常见；然而，它与更高的肿瘤侵袭性无关。
Cells. 2020 Feb 20;9(2):492. doi: 10.3390/cells9020492.

引用本文的文献

1
Rapid P-TEFb-dependent transcriptional reorganization underpins the glioma adaptive response to radiotherapy.快速 P-TEFb 依赖性转录重排为脑胶质瘤对放疗的适应性反应提供了基础。
Nat Commun. 2024 May 30;15(1):4616. doi: 10.1038/s41467-024-48214-3.

本文引用的文献

1
CDK8 maintains stemness and tumorigenicity of glioma stem cells by regulating the c-MYC pathway.CDK8 通过调控 c-MYC 通路维持神经胶质瘤干细胞的干性和致瘤性。
Oncogene. 2021 Apr;40(15):2803-2815. doi: 10.1038/s41388-021-01745-1. Epub 2021 Mar 16.
2
Therapeutic targeting of transcriptional elongation in diffuse intrinsic pontine glioma.弥漫性内生脑桥胶质瘤中转录延伸的治疗靶向。
Neuro Oncol. 2021 Aug 2;23(8):1348-1359. doi: 10.1093/neuonc/noab009.
3
Super Elongation Complex as a Targetable Dependency in Diffuse Midline Glioma.超级延伸复合物作为弥漫性中线胶质瘤的可靶向依赖性靶点。
Cell Rep. 2020 Apr 7;31(1):107485. doi: 10.1016/j.celrep.2020.03.049.
4
Profound, durable and MGMT-independent sensitivity of glioblastoma cells to cyclin-dependent kinase inhibition.胶质母细胞瘤细胞对细胞周期蛋白依赖性激酶抑制的深度、持久和 MGMT 独立性敏感性。
Int J Cancer. 2019 Jul 1;145(1):242-253. doi: 10.1002/ijc.32069. Epub 2019 Jan 12.
5
CDK7 inhibition is a novel therapeutic strategy against GBM both in vitro and in vivo.细胞周期蛋白依赖性激酶7（CDK7）抑制在体外和体内都是一种针对胶质母细胞瘤的新型治疗策略。
Cancer Manag Res. 2018 Nov 15;10:5747-5758. doi: 10.2147/CMAR.S183696. eCollection 2018.
6
Novel Targeting of Transcription and Metabolism in Glioblastoma.胶质母细胞瘤中转录和代谢的新靶点
Clin Cancer Res. 2018 Mar 1;24(5):1124-1137. doi: 10.1158/1078-0432.CCR-17-2032. Epub 2017 Dec 18.
7
Transcription elongation factors represent in vivo cancer dependencies in glioblastoma.转录延伸因子是胶质母细胞瘤体内的癌症依赖因素。
Nature. 2017 Jul 20;547(7663):355-359. doi: 10.1038/nature23000. Epub 2017 Jul 5.
8
Cyclin-dependent kinase 7 is a therapeutic target in high-grade glioma.细胞周期蛋白依赖性激酶7是高级别胶质瘤的一个治疗靶点。
Oncogenesis. 2017 May 15;6(5):e336. doi: 10.1038/oncsis.2017.33.
9
Transcriptional Dependencies in Diffuse Intrinsic Pontine Glioma.弥漫性脑桥内在型胶质瘤中的转录依赖性
Cancer Cell. 2017 May 8;31(5):635-652.e6. doi: 10.1016/j.ccell.2017.03.011. Epub 2017 Apr 20.
10
RBPJ maintains brain tumor-initiating cells through CDK9-mediated transcriptional elongation.RBPJ通过CDK9介导的转录延伸维持脑肿瘤起始细胞。
J Clin Invest. 2016 Jul 1;126(7):2757-72. doi: 10.1172/JCI86114. Epub 2016 Jun 20.

Converging evidence for inhibition of transcriptional control in high-grade gliomas.

作者信息

Dahl Nathan A, Vibhakar Rajeev

机构信息

Morgan Adams Foundation Pediatric Brain Tumor Research Program, Department of Pediatrics, University of Colorado School of Medicine, Aurora, Colorado, USA.

Pediatric Neuro-Oncology, Center for Cancer and Blood Disorders, Children's Hospital Colorado, Aurora, Colorado, USA.

出版信息

Neuro Oncol. 2021 Aug 2;23(8):1225-1227. doi: 10.1093/neuonc/noab112.

DOI:10.1093/neuonc/noab112
PMID:33984150
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8328005/
Abstract
摘要