Medstar Washington Hospital Center, Washington, DC, USA.
Georgetown University School of Medicine, Washington, DC, USA.
J Prim Care Community Health. 2021 Jan-Dec;12:21501327211017016. doi: 10.1177/21501327211017016.
Coronavirus infection (COVID) presents with flu-like symptoms and can cause serious complications. Here, we discuss the presentation and outcomes of COVID in an ambulatory setting along with distribution of positive cases amongst healthcare workers (HCWs).
Patients who visited the COVID clinic between 03/11/2020 and 06/14/2020 were tested based on the CDC guidelines at the time using PCR-detection methods. Medical records were reviewed and captured on a RedCap database. Statistical analysis was performed using both univariate and bivariate analysis using Fischer's exact test with 2-sided values.
Of the 2471 evaluated patients, 846 (34.2%) tested positive for COVID. Mean age of positivity was 43.4 years (SD ± 15.4), 60.1% were female and 49% were Black. 58.7% of people tested had a known exposure, and amongst those with exposure, 57.3% tested positive. Ninety-four patients were hospitalized (11.1%), of which 22 patients (23.4%) required ICU admission and 10 patients died. The overall death rate of patients presenting to clinic was 0.4%, or 1.2% amongst positive patients. Median length of hospital stay was 6 days (range 1-51). Symptoms significantly associated with COVID included: anosmia, fever, change in taste, anorexia, myalgias, cough, chills, and fatigue. Increased risk of COVID occurred with diabetes, whereas individuals with lung disease or malignancy were not associated with increased risk of COVID. Amongst COVID positive HCWs, the majority were registered nurses (23.4%), most working in general medicine (39.8%) followed by critical care units (14.3%).
DISCUSSION/CONCLUSION: Blacks and females had the highest infection rates. There was a broad range in presentation from those who are very ill and require hospitalization and those who remain ambulatory. The above data could assist health care professionals perform a targeted review of systems and co-morbidities, allowing for appropriate patient triage.
冠状病毒感染(COVID)表现为流感样症状,并可能导致严重并发症。在这里,我们讨论了在门诊环境中 COVID 的表现和结果,以及医护人员(HCWs)中阳性病例的分布情况。
根据当时 CDC 的指南,2020 年 3 月 11 日至 6 月 14 日期间,在 COVID 诊所就诊的患者使用 PCR 检测方法进行了检测。对病历进行了回顾,并在 RedCap 数据库中进行了记录。使用 Fisher 精确检验进行单变量和双变量分析,采用双侧检验。
在评估的 2471 名患者中,846 名(34.2%)COVID 检测呈阳性。阳性患者的平均年龄为 43.4 岁(标准差±15.4),60.1%为女性,49%为黑人。58.7%的人有已知的暴露,而在有暴露的人中,57.3%的人检测呈阳性。94 名患者住院(11.1%),其中 22 名(23.4%)需要 ICU 入院,10 名患者死亡。到诊所就诊的患者总死亡率为 0.4%,阳性患者为 1.2%。住院中位数为 6 天(范围 1-51)。与 COVID 相关的症状包括:嗅觉丧失、发热、味觉改变、食欲不振、肌痛、咳嗽、寒战和疲劳。糖尿病患者 COVID 风险增加,而患有肺部疾病或恶性肿瘤的患者 COVID 风险没有增加。在 COVID 阳性的 HCWs 中,大多数是注册护士(23.4%),大多数在普通医学科工作(39.8%),其次是重症监护病房(14.3%)。
讨论/结论:黑人女性感染率最高。从那些病情严重需要住院治疗到那些仍能活动的人,症状表现范围很广。上述数据可以帮助医疗保健专业人员对系统和合并症进行有针对性的审查,从而对患者进行适当的分诊。