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帕金森病中的睡眠障碍。

Sleep Disorders in Parkinson Disease.

机构信息

Department of Neurology, Medical University of Innsbruck, Anichstr. 35, Innsbruck 6020, Austria.

Department of Neurology, Medical University of Innsbruck, Anichstr. 35, Innsbruck 6020, Austria.

出版信息

Sleep Med Clin. 2021 Jun;16(2):323-334. doi: 10.1016/j.jsmc.2021.03.001. Epub 2021 Apr 15.

Abstract

Sleep disorders in Parkinson disease have attracted the attention of clinicians and researchers for decades. Recently, major advances in their clinical characterization, polysomnographic description, pathophysiologic understanding, and treatment took place. Parkinson disease encompasses the whole spectrum of sleep medicine: every category of sleep disorder can be observed in these patients. Video polysomnography frequently is indicated, sometimes followed by multiple sleep latency/maintenance of wakefulness tests. Additional studies may include actigraphy, cardiorespiratory polygraphy, and dim light melatonin assessment. Treatment needs to be specific to the underlying sleep disorder and can include medications and nondrug treatments, for example, behavioral therapy and light therapy.

摘要

几十年来,帕金森病患者的睡眠障碍一直受到临床医生和研究人员的关注。最近,在临床特征、多导睡眠描记术描述、病理生理学理解和治疗方面取得了重大进展。帕金森病涵盖了睡眠医学的各个方面:这些患者可能出现每一种类别的睡眠障碍。常需要进行视频多导睡眠图检查,有时还需要多次进行睡眠潜伏期/维持觉醒试验。其他研究可能包括活动记录仪、心肺多导睡眠描记术和暗光褪黑素评估。治疗需要针对潜在的睡眠障碍,并可包括药物和非药物治疗,例如行为疗法和光照疗法。

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