Barnwell J W, Desowitz R S
Ann Trop Med Parasitol. 1977 Dec;71(4):429-33. doi: 10.1080/00034983.1977.11687208.
White rats infected with Plasmodiam berghei were observed throughout the course of infection for indicators of impending crisis (penultimate stage). Two ratios, percentage young compact forms:percentage trophozoites and percentage reticulocytes:percentage parasitaemia, were reliable markers of the penultimate period and impending crisis. When the percentage young compact form:percentage trophozoite ratio exceeded 1.0 and was coincident with an increase of uninfected reticulocytes in the circulation (as given by a percentage reticulocyte:percentage parasitaemia ratio greater than 1.0) the parasitaemic decline of crisis consistently occurred 24-48 hours later.
在感染伯氏疟原虫的整个过程中，观察了白色大鼠即将出现危机（倒数第二阶段）的指标。两个比率，即年轻致密型百分比：滋养体百分比和网织红细胞百分比：寄生虫血症百分比，是倒数第二阶段和即将出现危机的可靠标志物。当年轻致密型百分比：滋养体比率超过1.0，且与循环中未感染网织红细胞的增加同时出现时（由网织红细胞百分比：寄生虫血症比率大于1.0给出），危机时的寄生虫血症下降通常在24 - 48小时后发生。
