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非脊柱手术后化脓性脊椎间盘炎的管理:一家三级医疗中心的经验

Management of Pyogenic Spondylodiscitis Following Nonspinal Surgeries: A Tertiary Care Center Experience.

作者信息

Hasan Ghazwan A, Raheem Hayder Q, Qutub Ahmed, Wais Yasameen Bani, Katran Mustafa Hayder, Shetty Gautam M

机构信息

Department of Orthopaedic Surgery, Al-Kindi Teaching Hospital, Baghdad, Iraq.

Al-Mustansiria Medical College, Baghdad, Iraq.

出版信息

Int J Spine Surg. 2021 Jun;15(3):591-599. doi: 10.14444/8080. Epub 2021 May 13.

Abstract

BACKGROUND

The literature is lacking on the incidence and management of pyogenic spondylodiscitis (PS) following routine elective surgical procedures. This study aimed to analyze the presentation and treatment outcome in patients with PS following nonspinal surgeries at a tertiary care center with a minimum follow-up of 12 months.

METHODS

The demographic, clinical-radiologic features, and treatment outcomes in 40 patients with a diagnosis of PS following nonspinal surgical procedures were retrospectively reviewed and analyzed.

RESULTS

The mean age at presentation was 36.4 ± 11.8 years, with 80% of patients being female. The common surgical procedures associated with PS were cesarean delivery (30%), gastric sleeve surgery (12.5%), and dilatation and curettage (12.5%). The tissue biopsy culture was positive in 82.5% of patients. A total of 26 patients (65%) were treated with conservative management and 14 patients (35%) were treated surgically. The mean pretreatment Core Outcome Measure Index score significantly decreased at 12 months ( < .0001) after treatment. The mean pretreatment erythrocyte sedimentation rate ( < .0001) and C-reactive protein ( < .0001) levels significantly decreased at 12 months after treatment.

CONCLUSIONS

With most patients with PS following nonspinal surgeries treated with conservative management, excellent clinical outcomes were achieved in all patients at 12 months after treatment. The diagnosis of PS should be considered in patients presenting with low back pain (LBP) with a recent history of undergoing a nonspinal surgical procedure. Patients who undergo surgical procedures are an important "at-risk" patient population, and early diagnosis and treatment can help achieve excellent clinical outcomes. Further studies are required to determine risk factors and possible perioperative precautions that can be taken to prevent PS in patients who undergo nonspine surgeries.

LEVEL OF EVIDENCE

CLINICAL RELEVANCE

Pyogenic spondylodiscitis should be suspected in patients presenting with LBP after a recent non-spinal surgical procedure. Early diagnosis and treatment can help achieve excellent clinical outcomes in these patients.

摘要

背景

关于常规择期手术后化脓性脊椎间盘炎(PS)的发病率及处理,文献报道较少。本研究旨在分析在一家三级医疗中心接受非脊柱手术后发生PS的患者的临床表现及治疗结果,随访时间至少为12个月。

方法

回顾性分析40例诊断为非脊柱手术后发生PS患者的人口统计学、临床放射学特征及治疗结果。

结果

患者就诊时的平均年龄为36.4±11.8岁,80%为女性。与PS相关的常见手术包括剖宫产(30%)、胃袖状切除术(12.5%)和刮宫术(12.5%)。82.5%的患者组织活检培养呈阳性。共有26例患者(65%)接受保守治疗,14例患者(35%)接受手术治疗。治疗后12个月时,平均治疗前核心结局指标评分显著降低(P<0.0001)。治疗后12个月时,平均治疗前红细胞沉降率(P<0. .0001)和C反应蛋白水平(P<0.0001)显著降低。

结论

大多数非脊柱手术后发生PS的患者接受保守治疗,治疗后12个月时所有患者均取得了良好的临床效果。对于近期有非脊柱手术史且出现腰痛(LBP)的患者,应考虑PS的诊断。接受手术的患者是重要的“高危”人群,早期诊断和治疗有助于取得良好的临床效果。需要进一步研究以确定风险因素以及在接受非脊柱手术的患者中预防PS可采取的围手术期预防措施。

证据级别

3级。

临床意义

近期非脊柱手术后出现LBP的患者应怀疑化脓性脊椎间盘炎。早期诊断和治疗有助于这些患者取得良好的临床效果。

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