使用基础胰岛素的2型糖尿病患者超基础胰岛素化的患病率及相关特征：一项横断面研究
Prevalence of and Characteristics Associated With Overbasalization Among Patients With Type 2 Diabetes Using Basal Insulin: A Cross-Sectional Study.
作者信息
Cowart Kevin, Updike Wendy H, Pathak Rashmi
机构信息
Department of Pharmacotherapeutics & Clinical Research, Taneja College of Pharmacy, University of South Florida, Tampa, FL.
Department of Internal Medicine, Morsani College of Medicine, University of South Florida, Tampa, FL.
出版信息
Clin Diabetes. 2021 Apr;39(2):173-175. doi: 10.2337/cd20-0080.
Abstract
This article describes a cross-sectional analysis of 655 patients to determine the prevalence of and patient-specific characteristics associated with overbasalization in patients with type 2 diabetes. Overbasalization was defined as uncontrolled A1C (>8%) plus a basal insulin dose >0.5 units/kg/day. The period prevalence of overbasalization was found to be 38.1, 42.7, and 42% for those with an A1C >8, ≥9, and ≥10%, respectively. Those with an A1C ≥9% had the greatest likelihood of experiencing overbasalization. These results suggest that overbasalization may play a role in patients not achieving optimal glycemic control in type 2 diabetes.
摘要
本文描述了一项对655例患者的横断面分析，以确定2型糖尿病患者中过度基础胰岛素治疗的患病率及相关的患者特异性特征。过度基础胰岛素治疗被定义为糖化血红蛋白（A1C）未得到控制（>8%）加上基础胰岛素剂量>0.5单位/千克/天。对于A1C>8%、≥9%和≥10%的患者，过度基础胰岛素治疗的期间患病率分别为38.1%、42.7%和42%。A1C≥9%的患者发生过度基础胰岛素治疗的可能性最大。这些结果表明，过度基础胰岛素治疗可能在2型糖尿病患者未实现最佳血糖控制中起作用。
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