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对从猫身上分离出的sp.CACC 737进行基因组分析以探讨其潜在应用。

Genome analysis of sp.CACC 737 isolated from feline for its potential application.

作者信息

Kim Jung-Ae, Jung Min Young, Kim Dae-Hyuk, Kim Yangseon

机构信息

Department of Research and Development, Center for Industrialization of Agricultural and Livestock Microorganisms, Jeongeup 56212, Korea.

Department of Bioactive Material Sciences, Jeonbuk National University, Jeonju 54896, Korea.

出版信息

J Anim Sci Technol. 2020 Nov;62(6):952-955. doi: 10.5187/jast.2020.62.6.952. Epub 2020 Nov 30.

DOI:10.5187/jast.2020.62.6.952
PMID:33987575
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7721585/
Abstract

sp. CACC 737 was isolated from a feline, and its potential probiotic properties were characterized using functional genome analysis. Whole-genome sequencing was performed using the PacBio RSII and Illumina HiSeq platforms. The complete genome of strain CACC 737 contained 4.6 Mb, with a guanine (G) + cytosine (C) content of 45.8%, six cryptic plasmids, and extracellular polysaccharide gene as unique features. The strain was beneficial to animal health when consumed as feed, for example, for ameliorating immunological dysfunctions and metabolic disorders. The genome information adds to the comprehensive understanding of sp. and suggests potential animal-related industrial applications for this strain.

摘要

菌株CACC 737是从一只猫身上分离得到的,利用功能基因组分析对其潜在的益生菌特性进行了表征。使用PacBio RSII和Illumina HiSeq平台进行全基因组测序。菌株CACC 737的完整基因组包含4.6 Mb,鸟嘌呤(G)+胞嘧啶(C)含量为45.8%,具有六个隐蔽质粒和胞外多糖基因,这些是其独特特征。当作为饲料食用时,该菌株对动物健康有益,例如,可改善免疫功能障碍和代谢紊乱。该基因组信息有助于对该菌株的全面了解,并表明该菌株在动物相关产业中具有潜在应用价值。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/caa4/7721585/9ff660bddd0a/jast-62-6-952-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/caa4/7721585/9ff660bddd0a/jast-62-6-952-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/caa4/7721585/9ff660bddd0a/jast-62-6-952-g1.jpg

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