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用于推导接受 CT 检查的犬科动物器官剂量的转换因子。

Conversion factors to derive organ doses for canine subjects undergoing CT examinations.

机构信息

Paul VI Catholic High School, Fairfax, Virginia, USA.

Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, Maryland, USA.

出版信息

Vet Radiol Ultrasound. 2021 Jul;62(4):421-428. doi: 10.1111/vru.12979. Epub 2021 May 14.

DOI:10.1111/vru.12979
PMID:33987905
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10789152/
Abstract

Although a large number of CT scans are being conducted on small animals, especially in Western countries, little is known of absorbed dose from veterinary CT scans. In the current retrospective analytical study, we estimated the radiation dose delivered to dogs from CT scans with various scan protocols and compared the results with those of human patients. We adopted a total of three computerized canine models with three sizes combined with a computer simulation model of a CT scanner. The eyes of the dog model received the greatest dose, 1.10 mGy/mGy, in the head scan, followed by a brain dose of 0.85 mGy/mGy. In the chest, abdomen-pelvis (AP), chest-abdomen-pelvis, and head-chest-abdomen-pelvis scans, the heart wall (0.93 mGy/mGy), ovaries (0.99 mGy/mGy), lungs (1.12 mGy/mGy), and thyroid (1.23 mGy/mGy) received the greatest organ doses, respectively. The smallest dog model received up to 1.4-fold greater organ doses than the largest dog in both the chest and AP scans. Overall, the medium-size canine model received organ doses comparable to those of the 1-year-old child model in the head scan, the 5-year-old child in chest scan, and the 10-year-old child in AP scan. The organ dose conversion factors derived from this study should help evaluate absorbed dose for canine patients undergoing CT exams.

摘要

尽管大量的 CT 扫描在小动物身上进行,尤其是在西方国家,但兽医 CT 扫描的吸收剂量知之甚少。在当前的回顾性分析研究中,我们估计了各种扫描方案下犬 CT 扫描的辐射剂量,并将结果与人类患者进行了比较。我们采用了总共三种大小的计算机化犬模型,并结合 CT 扫描仪的计算机模拟模型。在头部扫描中,犬模型的眼睛接收到最大剂量,为 1.10 mGy/mGy,其次是大脑剂量为 0.85 mGy/mGy。在胸部、腹部-骨盆 (AP)、胸部-腹部-骨盆和头部-胸部-腹部-骨盆扫描中,心脏壁 (0.93 mGy/mGy)、卵巢 (0.99 mGy/mGy)、肺 (1.12 mGy/mGy) 和甲状腺 (1.23 mGy/mGy) 分别接收到最大的器官剂量。最小的犬模型在胸部和 AP 扫描中接收到的器官剂量比最大的犬模型高出 1.4 倍。总体而言,中号犬模型在头部扫描中接收到的器官剂量与 1 岁儿童模型相当,在胸部扫描中接收到的器官剂量与 5 岁儿童相当,在 AP 扫描中接收到的器官剂量与 10 岁儿童相当。本研究得出的器官剂量转换因子应有助于评估接受 CT 检查的犬患者的吸收剂量。

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