VISN 2 Center of Excellence for Suicide Prevention, Department of Veterans Affairs, Finger Lakes Healthcare System, Canandaigua, New York.
Department of Psychiatry, University of Rochester School of Medicine and Dentistry, Rochester, New York.
J Clin Psychiatry. 2021 Feb 23;82(2):19m13228. doi: 10.4088/JCP.19m13228.
Risk for suicide is highest in the first 3 months (days 1-90) after discharge from acute psychiatric hospitalization yet remains elevated for the remainder of the year (days 91-365). The purpose of this study was to compare risk factors for suicide in the first 90 days to those over the remainder of the year to identify changes across time frames.
The study included 316,707 male veterans discharged from Veterans Health Administration acute psychiatric inpatient units from 2008 through 2013. Proportional hazard regression models were used to identify predictors of suicide death in the first 90 days and in days 91-365, defined via ICD-10 codes. Adjusted piecewise proportional hazard regression was used to compare risk across time frames.
Among the 1,037 veterans (< 1%) who died by suicide, 471 (45%) died between days 1 and 90 and 566 (55%) died between days 91 and 365. There was little change regarding the strength of risk factors over time, with two exceptions: risk increased among those aged 18-29 years compared to those aged ≥ 65 years (days 1-90: hazard ratio [HR] = 0.83; 95% CI, 0.57-1.20 vs days 91-365: HR = 1.42; 95% CI, 1.03-1.97; P < .05), whereas, risk associated with suicidal ideation decreased (days 1-90: HR = 1.89; 95% CI, 1.57-2.28 vs days 91-365: HR = 1.40; 95% CI, 1.17-1.66, P < .05).
The strength of association between common risk factors and suicide remains relatively stable during the year following psychiatric hospitalization. However, risk among veterans aged 19-29 years increased over time, whereas risk among those with suicidal ideation decreased.
从急性精神病住院出院后的头 3 个月(第 1-90 天)自杀风险最高,但在这一年的剩余时间(第 91-365 天)仍处于较高水平。本研究的目的是比较前 90 天和后 365 天自杀风险的危险因素,以确定随时间变化的差异。
该研究纳入了 2008 年至 2013 年期间从退伍军人健康管理局急性精神病住院部出院的 316,707 名男性退伍军人。使用比例风险回归模型来识别第 1-90 天和第 91-365 天自杀死亡的预测因素,通过 ICD-10 编码定义。使用分段比例风险回归来比较不同时间框架的风险。
在 1,037 名(<1%)自杀死亡的退伍军人中,有 471 人(45%)在第 1 天至第 90 天之间死亡,566 人(55%)在第 91 天至第 365 天之间死亡。随着时间的推移,风险因素的强度几乎没有变化,只有两个例外:与≥65 岁的人相比,18-29 岁的人风险增加(第 1-90 天:风险比[HR] = 0.83;95%可信区间,0.57-1.20 与第 91-365 天:HR = 1.42;95%可信区间,1.03-1.97;P < .05),而与自杀意念相关的风险降低(第 1-90 天:HR = 1.89;95%可信区间,1.57-2.28 与第 91-365 天:HR = 1.40;95%可信区间,1.17-1.66,P < .05)。
从精神病住院后一年期间,常见风险因素与自杀之间的关联强度相对稳定。然而,19-29 岁的退伍军人的风险随时间增加,而有自杀意念的人的风险降低。