Departmento de Ingeniería Química y Bioprocesos, Pontificia Universidad Católica de Chile, Santiago, Chile.
Centro Surcolombiano de Investigación en Café "CESURCAFÉ", Universidad Surcolombiana, Neiva, Colombia.
Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2021 Jul;38(7):1126-1135. doi: 10.1080/19440049.2021.1914867. Epub 2021 May 14.
This study estimates for the first time dietary acrylamide intake in Chile and conducts exposure risk assessments using the margin of exposure (MOE) method. A consumption frequency survey of starchy foods was carried out in the metropolitan region of Santiago, Chile on people from different socioeconomic levels aged between 12 and 65 years old. The acrylamide contents of the most frequently consumed foods were determined by an in-house validated GC-MS technique. The potatoes and bread group contributed ~77% to the dietary acrylamide exposure in Chile, with estimated daily mean exposure of 0.55 µg kg day and 0.22 µg kg day, respectively. Chilean population aged between 12 and 17 years old presented the highest acrylamide intake (mean, 1.27 µg kg day; 95th percentile, 3.90 µg kg day). Finally, since the estimated MOEs were lower than 10,000, the dietary acrylamide exposure in the metropolitan region of Santiago, Chile is of public health concern according to the EFSA criteria.
本研究首次估算了智利的饮食丙烯酰胺摄入量，并使用暴露量评估方法（MOE）进行了暴露风险评估。在智利圣地亚哥大都市区，对不同社会经济水平的 12 至 65 岁人群进行了淀粉类食品消费频率调查。通过内部验证的 GC-MS 技术测定了最常食用食品中的丙烯酰胺含量。土豆和面包组对智利饮食中丙烯酰胺的暴露量贡献了约 77%，其日平均摄入量分别为 0.55µg kg day 和 0.22µg kg day。12 至 17 岁的智利人摄入的丙烯酰胺最多（平均值为 1.27µg kg day；95%分位数为 3.90µg kg day）。最后，由于估计的 MOE 低于 10000，根据 EFSA 的标准，圣地亚哥大都市区的智利饮食丙烯酰胺暴露对公共健康构成了关注。
