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一例家族性非典型阿尔茨海默病:淀粉样P成分的免疫组织化学研究

A case of familial, atypical Alzheimer's disease: immunohistochemical study of amyloid P-component.

作者信息

Iseki E, Amano N, Matsuishi T, Yokoi S, Arai N, Yagishita S

机构信息

Department of Psychiatry and Neurology, Yokohama City University School of Medicine, Japan.

出版信息

Neuropathol Appl Neurobiol. 1988 Mar-Apr;14(2):169-74. doi: 10.1111/j.1365-2990.1988.tb00878.x.

Abstract

The presence of amyloid P-component (AP) in the amyloid plaques of a case of familial, atypical Alzheimer's disease was examined by means of the anti-AP immunoperoxidase method. Many amyloid plaques stained strongly positive for AP, so that they were analogous in AP stainability to those of Creutzfeldt-Jakob disease.

摘要

采用抗淀粉样蛋白P成分(AP)免疫过氧化物酶法,检测了1例家族性非典型阿尔茨海默病患者淀粉样斑块中AP的存在情况。许多淀粉样斑块对AP呈强阳性染色,因此它们在AP染色性方面与克雅氏病的淀粉样斑块相似。

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