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全膝关节置换术比全髋关节置换术引起更大的术后即刻疼痛和阿片类药物使用。

Total knee arthroplasty is associated with greater immediate post-surgical pain and opioid use than total hip arthroplasty.

机构信息

New York University Langone Orthopaedic Hospital, 301 East 17 St, Manhattan, New York, NY, 10003, USA.

出版信息

Arch Orthop Trauma Surg. 2022 Dec;142(12):3575-3580. doi: 10.1007/s00402-021-03951-8. Epub 2021 May 15.

Abstract

BACKGROUND

As greater emphasis is being placed on opioid reduction strategies and implementation of multimodal analgesia, we sought to determine whether immediate post-surgical opioid consumption was different between THA and TKA.

METHODS

A single-institution total joint arthroplasty database was used to identify patients who underwent elective THA and TKA from 2016 to July 2019. Baseline demographic data, operative time (defined by incision time), and American Society of Anesthesiologist (ASA) class were collected. Morphine milligram equivalents (MME) were calculated and derived from prospectively documented nursing opioid administration events, while visual analog scale (VAS) scores represented pain levels, both of which were collected as part of our institution's standard protocols. Activity Measure for Post-Acute Care (AMPAC) was used to determine physical therapy progress.

RESULTS

A total of 11,693 cases were identified: 5,909 THA (50.53%) and 5784 (49.47%) TKA. THA patients tended to be slightly younger (63.38 years, SD 11.61 years, vs 65.72 years, SD 9.56 years; p < 0.01) and have lower BMIs (28.92 kg/m vs 32.52 kg/m; p < 0.01). THA patients had lower ASA scores in comparison to TKA patients (p < 0.01). Aggregate opioid consumption (93.76 MME vs 147.55 MME; p < 0.01) along with first 24-h and 48-h usage was significantly less for THA as compared to TKA. Similarly, mean pain scores (4.15 vs 5.08; p < 0.01) were lower for THA, while AMPAC mobilization scores were higher (20.88 vs 19.29; p < 0.01) when compared to TKA.

CONCLUSION

THA patients reported lower pain scores and were found to require less opioid medication in the immediate post-surgical period than TKA patients.

摘要

背景

随着对减少阿片类药物策略和实施多模式镇痛的重视度不断提高,我们试图确定全髋关节置换术(THA)和全膝关节置换术(TKA)之间术后即刻阿片类药物的消耗是否存在差异。

方法

我们使用单机构全关节置换数据库,确定了 2016 年至 2019 年 7 月期间接受择期 THA 和 TKA 的患者。收集了基线人口统计学数据、手术时间(定义为切口时间)和美国麻醉医师协会(ASA)分级。计算了吗啡毫克当量(MME),并从前瞻性记录的护理阿片类药物给药事件中得出,而视觉模拟评分(VAS)则代表疼痛水平,这两者均作为我们机构标准方案的一部分收集。术后康复活动量表(AMPAC)用于确定物理治疗进展。

结果

共确定了 11693 例患者:5909 例 THA(50.53%)和 5784 例 TKA(49.47%)。THA 患者的年龄略小(63.38 岁,标准差 11.61 岁,vs 65.72 岁,标准差 9.56 岁;p < 0.01),体重指数(BMI)较低(28.92 kg/m 2 vs 32.52 kg/m 2;p < 0.01)。THA 患者的 ASA 评分低于 TKA 患者(p < 0.01)。与 TKA 相比,THA 患者的总体阿片类药物消耗量(93.76 MME 与 147.55 MME;p < 0.01)以及术后前 24 小时和 48 小时的用量明显减少。同样,THA 患者的平均疼痛评分(4.15 分与 5.08 分;p < 0.01)较低,而术后康复活动量表(AMPAC)评分较高(20.88 分与 19.29 分;p < 0.01)。

结论

THA 患者报告的疼痛评分较低,并且在术后即刻阶段需要的阿片类药物少于 TKA 患者。

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