Mogalli Abdullah S, Zhao Jianbo, Chen Yang, Qi Xin
Department of Bone and Joint Surgery, Orthopaedic Center, The First Hospital of Jilin University, Xin-Min Street No. 1, Changchun, 130021, Jilin, China.
Int Orthop. 2025 Jan;49(1):53-63. doi: 10.1007/s00264-024-06342-x. Epub 2024 Oct 10.
To evaluate the efficacy of blood management in patients underwent unilateral Total Knee Arthroplasty (TKA) under an enhanced recovery after surgery (ERAS) program.
Patients underwent unilateral TKA from January 2019 to October 2023 in a university hospital were retrospectively studied. A total of 200 cases were selected in the analysis. After matching with propensity scoring, 51 patients in each group were included. The postoperative Haemoglobin (Hb), albumin (Alb), C-reactive protein (CRP), total length of stay (LOS), and estimated blood loss after operation were compared between the two groups. Clinical outcomes including Western Ontario and McMaster Universities Arthritis Index (WOMAC), SF-12, and Oxford Knee Score (OKS) were also compared at six week and three month follow-up.
The results showed that the Hb of the ERAS group was significantly higher than those of the non-ERAS group (P < 0.05) on the third postoperative. The mean CRP level was lower, LOS was shorter, and Alb level was higher in the ERAS group compared to that in the non-ERAS group (P < 0.05). The clinical outcomes such as WOMAC and OKS, SF-12 scores were higher in the ERAS group at both follow-up.
ERAS protocol effectively minimizes perioperative blood loss and supports optimal nutrient levels in patients. ERAS management significantly contributes to the postoperative recovery of knee function in patients undergoing primary total knee arthroplasty.
评估在术后加速康复(ERAS)方案下,单侧全膝关节置换术(TKA)患者血液管理的疗效。
回顾性研究2019年1月至2023年10月在某大学医院接受单侧TKA的患者。分析中共选取200例病例。经倾向评分匹配后,每组纳入51例患者。比较两组患者术后血红蛋白(Hb)、白蛋白(Alb)、C反应蛋白(CRP)、住院总时长(LOS)及术后估计失血量。在术后六周和三个月随访时,还比较了包括西安大略和麦克马斯特大学关节炎指数(WOMAC)、SF-12和牛津膝关节评分(OKS)在内的临床结局。
结果显示,术后第三天,ERAS组的Hb显著高于非ERAS组(P<0.05)。与非ERAS组相比,ERAS组的平均CRP水平更低,LOS更短,Alb水平更高(P<0.05)。在两次随访中,ERAS组的WOMAC、OKS、SF-12等临床结局评分均更高。
ERAS方案有效减少了围手术期失血,并维持患者最佳营养水平。ERAS管理对初次全膝关节置换术患者的膝关节功能术后恢复有显著贡献。