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老年患者医疗干预程度:决策因素与死亡率的相关性。

Level of Medical Intervention in Geriatric Settings: Decision Factors and Correlation With Mortality.

机构信息

Service de médecine interne gériatrie, Pôle Personnes Agées, Centre Hospitalier Universitaire, Dijon, Bourgogne Franche-Comté, France.

Service de médecine interne gériatrie, Pôle Personnes Agées, Centre Hospitalier Universitaire, Dijon, Bourgogne Franche-Comté, France; Institut National de la Santé et de la Recherche Médicale U1093 Cognition Action Plasticité, Université de Bourgogne Franche-Comté, Dijon, Bourgogne Franche-Comté, France.

出版信息

J Am Med Dir Assoc. 2021 Dec;22(12):2587-2592. doi: 10.1016/j.jamda.2021.04.014. Epub 2021 May 14.

Abstract

OBJECTIVES

Level of medical intervention (LMI) has to be adapted to each patient in geriatric care. LMI scales intend to help nonintensive care (NIC) decisions, giving priority to patient choice and collegial discussion. In the present study, we aimed to assess the parameters associated with the NIC decision and whether these parameters differ from those associated with in-hospital mortality.

DESIGN

Prospective observational study.

SETTING AND PARTICIPANTS

All consecutive patients from a French 62-bed acute geriatric unit over 1 year.

METHODS

Factors from the geriatric assessment associated with the decision of NIC were compared with those associated with in-hospital and 1-year mortality, in univariate and multivariate analyses.

RESULTS

In total, 1654 consecutive patients (median age 87 years) were included. Collegial reflection led to NIC decision for 532 patients (32%). In-hospital and 1-year mortality were 22% and 54% in the NIC group vs 2% and 27% in the rest of the cohort (P < .001 for both). In multivariable analysis, high Charlson Comorbidity Index [odds ratio (OR) 1.15, 95% confidence interval (CI) 1.06-1.23, per point], severe neurocognitive disorders (OR 2.78, 95% CI 1.67-4.55), dependence (OR 1.92, 95% CI 1.45-2.59), and nursing home residence (OR 2.38, 95% CI 1.85-3.13) were highly associated with NIC decision but not with in-hospital mortality. Conversely, acute diseases had little impact on LMI despite their high short-term prognostic burden.

CONCLUSIONS AND IMPLICATIONS

Neurocognitive disorders and dependence were strongly associated with NIC decision, even though they were not significantly associated with in-hospital mortality. The decision-making process of LMI therefore seems to go beyond the notion of short-term survival.

摘要

目的

在老年护理中,医疗干预水平(LMI)必须根据每位患者的情况进行调整。LMI 量表旨在帮助非重症监护(NIC)决策,优先考虑患者的选择和同事间的讨论。在本研究中,我们旨在评估与 NIC 决策相关的参数,以及这些参数是否与院内死亡率相关的参数不同。

设计

前瞻性观察性研究。

地点和参与者

在法国一个有 62 张病床的急性老年病房,连续 1 年的所有患者。

方法

将与 NIC 决策相关的老年评估因素与院内和 1 年死亡率相关的因素进行比较,采用单因素和多因素分析。

结果

共纳入 1654 例连续患者(中位年龄 87 岁)。有 532 例(32%)经同事间讨论后决定接受 NIC。NIC 组的院内和 1 年死亡率分别为 22%和 54%,而其余队列分别为 2%和 27%(均<0.001)。多因素分析显示,Charlson 合并症指数较高(比值比 1.15,95%置信区间 1.06-1.23,每增加 1 分)、严重神经认知障碍(比值比 2.78,95%置信区间 1.67-4.55)、依赖(比值比 1.92,95%置信区间 1.45-2.59)和疗养院居住(比值比 2.38,95%置信区间 1.85-3.13)与 NIC 决策高度相关,但与院内死亡率无关。相反,尽管急性疾病具有较高的短期预后负担,但对 LMI 的影响较小。

结论和意义

神经认知障碍和依赖与 NIC 决策密切相关,尽管它们与院内死亡率无显著相关性。因此,LMI 的决策过程似乎超越了短期生存的概念。

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