Hoversten Patrick, Lomeli Luis, Broman Aimee Teo, Gaumnitz Eric, Hillman Luke
Department of Medicine, Division of Gastroenterology and Hepatology, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.
Department of Biostatistics and Medical Informatics, University of Wisconsin-Madison, Madison, WI, USA.
Dis Esophagus. 2023 Feb 24;36(3). doi: 10.1093/dote/doac054.
Many patients who experience esophageal food impaction (EFI) will have non-endoscopic resolution (NER) of their EFI, but this population is poorly defined. The purpose of this study is to describe the outcomes of patients with NER of EFI. A retrospective chart review from 2007 to 2017 was performed at a single tertiary care center. There were 593 patients who presented to the emergency department with EFI, defined as recent soft food ingestion and inability to tolerate oral secretions. Adequate follow-up was defined as a gastroenterology clinic visit or EGD within 6 months of EFI. Out of these, 149 patients (25.1%) had NER of their EFI. Patients with NER were less likely to have adequate follow-up than those with ER (45.0% vs. 59.5%, P = 0.003). Of those without established esophageal disease and NER, 92.5% had significant esophageal pathology on endoscopy, including stricture (34.0%), features of eosinophilic esophagitis (30.2%), and esophagitis (22.6%). Recurrent EFI occurred at a similar rate between patients with NER and ER (9.4% vs. 14.6%, P = 0.14). Patients with established esophageal disease (odds ratio [OR]: 1.51, P = 0.04) and recommendation to follow-up at time of EFI (OR: 6.06, P < 0.001) were most likely to follow up after EFI. Approximately, a quarter of patients with EFI will experience NER of their EFI. Virtually, all patients (92.5%) were found to have esophageal disease warranting longitudinal care. Importantly, follow-up rates are significantly lower in those with NER than their counterparts requiring EGD. Our study highlights the need to develop standardized protocols that improve follow-up for patients after NER of EFI.
许多经历食管食物嵌塞(EFI)的患者其EFI会通过非内镜方式缓解(NER),但这一人群的定义并不明确。本研究的目的是描述EFI经NER治疗患者的结局。在一家三级医疗中心对2007年至2017年的病历进行了回顾性分析。共有593例因EFI就诊于急诊科的患者,EFI定义为近期摄入软食且无法耐受口腔分泌物。充分随访定义为在EFI发生后6个月内进行胃肠病门诊就诊或接受内镜检查(EGD)。其中,149例患者(25.1%)的EFI实现了NER。与接受内镜治疗(ER)的患者相比,NER患者获得充分随访的可能性更小(45.0%对59.5%,P = 0.003)。在没有确诊食管疾病且实现NER的患者中,92.5%在内镜检查时发现有明显的食管病变,包括狭窄(34.0%)、嗜酸性食管炎特征(30.2%)和食管炎(22.6%)。NER患者和ER患者的复发性EFI发生率相似(9.4%对14.6%,P = 0.14)。确诊有食管疾病的患者(优势比[OR]:1.51,P = 0.04)以及在EFI时被建议进行随访的患者(OR:6.06,P < 0.001)在EFI后最有可能进行随访。大约四分之一的EFI患者其EFI会实现NER。实际上,所有患者(9