Laboratory of Green Synthesis, Department of Chemistry, University of Allahabad, Prayagraj, 211002, India.
Department of Chemistry, University of Delhi, New Delhi, India.
Mol Divers. 2022 Apr;26(2):1259-1266. doi: 10.1007/s11030-021-10228-0. Epub 2021 May 16.
A convenient and metal-free synthesis of vinyloxyimidazopyridine derivatives has been attained via BF.OEt promoted one-pot multicomponent approach. This procedure involves a facile coupling of 2-aminopyridine derivatives with arylglyoxal and alkyne derivatives. BF.OEt complexation has successfully catalyzed the reaction at room temperature. Utilization of transition metal-free catalyst, mild reaction conditions, easy handling and operational simplicity are key features of developed process.
通过 BF.OEt 促进的一锅多组分方法，方便且无需金属的合成了乙烯氧基咪唑并吡啶衍生物。该方法涉及 2-氨基吡啶衍生物与芳基乙二醛和炔烃衍生物的简便偶联。BF.OEt 络合物在室温下成功催化了反应。该过程的关键特点是使用无过渡金属催化剂、温和的反应条件、易于操作和操作简单。
