Institute of Animal Molecular Biotechnology and Department of Biotechnology, College of Life Sciences and Biotechnology, Korea University, Seoul 02841, Republic of Korea.
Department of Food and Nutrition, Kookmin University, Seoul 02707, Republic of Korea.
Pestic Biochem Physiol. 2021 Jun;175:104850. doi: 10.1016/j.pestbp.2021.104850. Epub 2021 Apr 7.
The increase in the size of the global population increases the food and energy demand, making the use of pesticides in agricultural and livestock industries unavoidable. Exposure to pesticides can be toxic to the non-target species, such as humans, wildlife, and livestock, in addition to the target organisms. Various chemicals are used in the livestock industry to control harmful organisms, such as insects, weeds, and parasites. Pigs are one of the most important food sources for humans. In addition, pigs can be used as promising models for assessing the risk of absorption of environmental pollutants through the skin and oral exposure since they are physiologically similar to humans. Exposure to numerous environmental pollutants, such as mycotoxins, persistent organic pollutants, and heavy metals, has been reported to adversely affect growth, fertility, and endocrine homeostasis in pigs. Various pesticides have been observed in porcine tissues, blood, urine, and processed foods; however, there is a lack of comprehensive understanding of their effects on porcine health. This review provides a comprehensive description of the characteristics of pesticides that pigs can be exposed to and how their exposure affects porcine reproductive function, intestinal health, and endocrine homeostasis in vivo and in vitro.
全球人口的增长增加了对食物和能源的需求，使得农业和畜牧业中使用农药不可避免。除了目标生物外，接触农药对非目标物种（如人类、野生动物和牲畜）也可能有毒。畜牧业中使用各种化学物质来控制有害生物，如昆虫、杂草和寄生虫。猪是人类最重要的食物来源之一。此外，猪可以作为评估通过皮肤和口腔暴露吸收环境污染物风险的有前途的模型，因为它们在生理上与人类相似。接触许多环境污染物，如霉菌毒素、持久性有机污染物和重金属，已被报道会对猪的生长、繁殖力和内分泌平衡产生不利影响。已经在猪组织、血液、尿液和加工食品中观察到各种农药，但对它们对猪健康的影响缺乏全面的了解。本综述全面描述了猪可能接触到的农药的特性，以及它们的接触如何影响猪的生殖功能、肠道健康和体内外的内分泌平衡。
