Department of Obstetrics and Gynecology, Center for Perinatal Medicine, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan.
Department of Obstetrics and Gynecology, Center for Perinatal Medicine, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan.
J Infect Chemother. 2021 Sep;27(9):1369-1372. doi: 10.1016/j.jiac.2021.04.021. Epub 2021 May 11.
Group B streptococcus (GBS) is an important pathogen that causes neonatal sepsis and meningitis, which have high mortality and morbidity. Cellulitis is a rare presentation of late-onset neonatal GBS infection. We report the case of an extremely low birthweight infant with facial cellulitis caused by late-onset GBS infection. A 590-g male neonate was delivered by Cesarean section at 23 gestational weeks due to intrauterine GBS infection. Although he was effectively treated with 2 weeks of antimicrobial therapy for early-onset GBS sepsis, he subsequently developed facial and submandibular cellulitis caused by GBS at 44 days of age. He was treated with debridement and antibiotic therapy, and after 2 months his facial involvement had improved, but cosmetic issues remained. Neonatal GBS infection requires a prompt sepsis workup followed by the initiation of empiric antibiotic therapy. Additionally, lifesaving surgical debridement is sometimes necessary for cellulitis, even in premature infants.
B 群链球菌（GBS）是一种重要的病原体，可导致新生儿败血症和脑膜炎，具有较高的死亡率和发病率。蜂窝织炎是晚发型新生儿 GBS 感染的罕见表现。我们报告了一例极低出生体重儿因晚发型 GBS 感染导致面部蜂窝织炎的病例。一名 590 克的男性新生儿因宫内 GBS 感染于 23 孕周行剖宫产术分娩。尽管他因早发型 GBS 败血症接受了 2 周的抗菌治疗，但随后在 44 天时出现了由 GBS 引起的面部和颌下蜂窝织炎。他接受了清创术和抗生素治疗，2 个月后他的面部受累情况有所改善，但仍存在美容问题。新生儿 GBS 感染需要及时进行败血症检查，然后开始经验性抗生素治疗。此外，即使是早产儿，蜂窝织炎有时也需要进行救命性的外科清创术。
