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瘦体重和脂肪体重均与血压相关。

Both lean and fat body mass associate with blood pressure.

作者信息

Korhonen Päivi E, Mikkola Tuija, Kautiainen Hannu, Eriksson Johan G

机构信息

Department of General Practice, Turku University and Turku University Hospital, Turku, Finland.

Folkhälsan Research Center, Helsinki, Finland; Clinicum, Faculty of Medicine, University of Helsinki, Finland.

出版信息

Eur J Intern Med. 2021 Sep;91:40-44. doi: 10.1016/j.ejim.2021.04.025. Epub 2021 May 13.

Abstract

High body mass index (BMI) is known to be associated with elevated blood pressure (BP). The present study aims to determine the relative importance of the two components of BMI, fat mass and lean body mass index, on BP levels. We assessed body composition with bioimpedance and performed 24 hour ambulatory BP measurements in 534 individuals (mean age 61 ± 3 years) who had no cardiovascular medication. Fat mass index and lean mass index were calculated analogously to BMI as fat mass or lean body mass (kg) divided by the square of height (m). Both fat mass index and lean mass index showed a positive, small to moderate relationship with all 24 hour BP components independently of age, sex, smoking, and leisure-time physical activity. There were no interaction effects between fat mass index and lean mass index on the mean BP levels. Adult lean body mass is a significant determinant of BP levels with an equal, albeit small to moderate magnitude as fat mass. Relatively high amount of muscle mass may not be beneficial to cardiovascular health.

摘要

众所周知,高体重指数(BMI)与血压升高有关。本研究旨在确定BMI的两个组成部分,即脂肪量和瘦体重指数,对血压水平的相对重要性。我们采用生物电阻抗法评估身体成分,并对534名未服用心血管药物的个体(平均年龄61±3岁)进行了24小时动态血压测量。脂肪量指数和瘦体重指数的计算方法与BMI类似,即脂肪量或瘦体重(千克)除以身高(米)的平方。脂肪量指数和瘦体重指数均与所有24小时血压成分呈正相关,且独立于年龄、性别、吸烟和休闲体育活动。脂肪量指数和瘦体重指数对平均血压水平没有交互作用。成年瘦体重是血压水平的一个重要决定因素,其影响程度与脂肪量相当,尽管是小到中等程度。相对较高的肌肉量可能对心血管健康并无益处。

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