Key Laboratory of Molecular Epidemiology of Hunan Province, School of Medicine, Hunan Normal University, Changsha, 410081, China.
BMC Pediatr. 2024 Sep 6;24(1):566. doi: 10.1186/s12887-024-05029-x.
For youths, abnormalities in ambulatory blood pressure (ABP) patterns are known to be associated with increased cardiovascular disease risk and potential target organ damage. Body composition, including indicators such as lean mass index (LMI), fat mass index (FMI), and visceral fat level (VFL), plays a significant role in blood pressure (BP) regulation. However, little is known about the association between these body composition indicators and ABP. Therefore, the present study examined the association between these body composition indicators and BP among Chinese youths.
A total of 477 college students aged 17 to 28 years old (mean ± Standard deviation = 18.96 ± 1.21) from a university in Changsha, Hunan Province, China, were included in this study. Body composition indicators were measured with a bioelectrical impedance body composition analyzer, and 24-hour ambulatory blood pressure monitoring (ABPM) was conducted. Multivariable logistic regression was performed to assess the relationship between body composition indicators and abnormal ABP.
The prevalence of abnormal BP, including 24-hour BP, daytime BP, nighttime BP, and clinic BP, were 4.8%, 4.2%, 8.6%, and 10.9%, respectively. After adjusting for potential covariates, LMI [abnormal 24-hour BP (OR = 1.85, 95%CI:1.31, 2.62), abnormal daytime BP (OR = 1.76, 95%CI:1.21, 2.58), abnormal nighttime BP (OR = 1.64, 95%CI:1.25, 2.14), abnormal clinic BP (OR = 1.84, 95%CI:1.38, 2.45)], FMI [abnormal 24-hour BP (OR = 1.20, 95%CI:1.02, 1.41), abnormal daytime BP (OR = 1.30, 95%CI:1.07, 1.57), abnormal nighttime BP (OR = 1.24, 95%CI:1.10, 1.39), abnormal clinic BP (OR = 1.42, 95%CI:1.22, 1.65)], and VFL [abnormal 24-hour BP (OR = 1.22, 95%CI:1.06, 1.39), abnormal daytime BP (OR = 1.29, 95%CI:1.10, 1.51), abnormal nighttime BP (OR = 1.24, 95%CI:1.12, 1.39), abnormal clinic BP (OR = 1.38, 95%CI:1.21, 1.57)] are positively linked to abnormal BP. Additionally, there were significant sex differences in the association between body composition and abnormal BP.
Our findings suggested maintaining an individual's appropriate muscle mass and fat mass and focusing on the different relations of males' and females' body composition is crucial for the achievement of appropriate BP profiles.
对于年轻人来说，动态血压（ABP）模式的异常与心血管疾病风险增加和潜在的靶器官损害有关。身体成分，包括瘦体重指数（LMI）、体脂指数（FMI）和内脏脂肪水平（VFL）等指标，在血压（BP）调节中起着重要作用。然而，关于这些身体成分指标与 ABP 之间的关联知之甚少。因此，本研究旨在探讨中国年轻人中这些身体成分指标与 BP 之间的关系。
共纳入 477 名年龄在 17 至 28 岁（均值±标准差=18.96±1.21）的来自中国湖南省长沙市某大学的大学生。使用生物电阻抗体成分分析仪测量身体成分指标，并进行 24 小时动态血压监测（ABPM）。采用多变量逻辑回归评估身体成分指标与异常 ABPM 之间的关系。
异常血压的患病率分别为：24 小时 BP（4.8%）、日间 BP（4.2%）、夜间 BP（8.6%）和诊室 BP（10.9%）。在校正潜在协变量后，LMI[异常 24 小时 BP（OR=1.85，95%CI：1.31，2.62）、异常日间 BP（OR=1.76，95%CI：1.21，2.58）、异常夜间 BP（OR=1.64，95%CI：1.25，2.14）、异常诊室 BP（OR=1.84，95%CI：1.38，2.45）]、FMI[异常 24 小时 BP（OR=1.20，95%CI：1.02，1.41）、异常日间 BP（OR=1.30，95%CI：1.07，1.57）、异常夜间 BP（OR=1.24，95%CI：1.10，1.39）、异常诊室 BP（OR=1.42，95%CI：1.22，1.65）]和 VFL[异常 24 小时 BP（OR=1.22，95%CI：1.06，1.39）、异常日间 BP（OR=1.29，95%CI：1.10，1.51）、异常夜间 BP（OR=1.24，95%CI：1.12，1.39）、异常诊室 BP（OR=1.38，95%CI：1.21，1.57）]与异常 BP 呈正相关。此外，身体成分与异常 BP 之间的关联存在显著的性别差异。
我们的研究结果表明，保持个体适当的肌肉量和脂肪量，并关注男性和女性身体成分的不同关系，对于实现适当的 BP 谱至关重要。
