Department of Medical and Surgical Sciences - Rheumatology Unit, University of Foggia, Italy.
J Med Invest. 2021;68(1.2):6-14. doi: 10.2152/jmi.68.6.
Nailfold video-capillaroscopy (NVC) is a useful diagnostic tool, used to early detect abnormalities in micro-circulation, providing a qualitative description of microvascular anomalies in Raynaud's phenomenon. NVC role in the diagnosis of Systemic Sclerosis is well known. In other rheumatic conditions such as connective tissue diseases, vasculitis, and arthritis, the NVC anomalies are often included in a scleroderma like pattern. The use of NVC in non-rheumatic diseases (NRD), with remarkable microvascular damage, as diabetes, is not standardized yet, although several research studies are carrying on. The aim of this article is to provide a resume of published results in order to lay the groundwork for the employment of NVC both in the diagnosis and follow up of microvascular complication in NRD. Furthermore, we mention NVC findings in pathologies without well recognize microvascular damages in their pathogenesis : micro-vessels abnormalities may suggest a different point of view. J. Med. Invest. 68 : 6-14, February, 2021.
甲襞微循环视频检查（NVC）是一种有用的诊断工具，用于早期发现微循环异常，提供雷诺现象中小血管异常的定性描述。NVC 在系统性硬化症的诊断中的作用是众所周知的。在其他风湿性疾病（如结缔组织疾病、血管炎和关节炎）中，NVC 异常通常包括在硬皮病样模式中。NVC 在非风湿性疾病（NRD）中的应用，尽管有几项研究正在进行，但仍未标准化，这些疾病具有显著的微血管损伤，如糖尿病。本文的目的是总结已发表的研究结果，为 NVC 在 NRD 的微血管并发症的诊断和随访中的应用奠定基础。此外，我们还提到了在发病机制中没有明确认识到微血管损伤的病理中的 NVC 发现：小血管异常可能提示不同的观点。医学研究杂志 68：6-14，2021 年 2 月。
