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通过甲襞毛细血管镜检查记录的COVID-19微血管改变。

Microvascular Alteration in COVID-19 Documented by Nailfold Capillaroscopy.

作者信息

Mondini Lucrezia, Confalonieri Paola, Pozzan Riccardo, Ruggero Luca, Trotta Liliana, Lerda Selene, Hughes Michael, Bellan Mattia, Confalonieri Marco, Ruaro Barbara, Salton Francesco, Tavano Stefano

机构信息

Pulmonology Unit, Department of Medical Surgical and Health Sciences, University Hospital of Cattinara, University of Trieste, 34149 Trieste, Italy.

Graduate School, University of Milan, 20149 Milano, Italy.

出版信息

Diagnostics (Basel). 2023 May 29;13(11):1905. doi: 10.3390/diagnostics13111905.

Abstract

COVID-19 is a multisystemic disease that mainly affects and causes dysregulation of the endothelium, causing systemic manifestations. A nailfold video capillaroscopy is a safe, easy, and noninvasive method to evaluate microcirculation alteration. In this review, we analyzed the literature available to date regarding the object of nailfold video capillaroscopy (NVC) use in patients with a SARS-CoV-2 infection, both in the acute phase and after discharge. The scientific evidence pointed out the main alterations in capillary circulation shown by NVC, so reviewing the findings of each article allowed us to define and analyze the future prospects and needs for possibly including NVC within the management of patients with COVID-19, both during and after the acute phase.

摘要

新冠病毒病是一种多系统疾病,主要影响内皮细胞并导致其功能失调,从而引发全身症状。甲襞视频毛细血管镜检查是一种评估微循环改变的安全、简便且无创的方法。在本综述中,我们分析了迄今为止关于在急性感染期及出院后使用甲襞视频毛细血管镜检查(NVC)评估严重急性呼吸综合征冠状病毒2(SARS-CoV-2)感染患者的相关文献。科学证据指出了NVC所显示的毛细血管循环的主要改变,因此回顾每篇文章的研究结果使我们能够确定并分析将NVC纳入新冠病毒病患者急性期及急性期后管理的未来前景和需求。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/93a6/10252666/f537ea95286f/diagnostics-13-01905-g001.jpg

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