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本文引用的文献

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Complications on minimally invasive oblique lumbar interbody fusion at L2-L5 levels: a review of the literature and surgical strategies.L2-L5节段微创斜外侧腰椎椎间融合术的并发症:文献综述与手术策略
Ann Transl Med. 2018 Mar;6(6):101. doi: 10.21037/atm.2018.01.22.
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Pseudarthrosis in adult and pediatric spinal deformity surgery: a systematic review of the literature and meta-analysis of incidence, characteristics, and risk factors.成人及儿童脊柱畸形手术中的假关节形成:文献系统综述及发病率、特征和危险因素的荟萃分析
Neurosurg Rev. 2019 Jun;42(2):319-336. doi: 10.1007/s10143-018-0951-3. Epub 2018 Feb 6.
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The Effect of Smoking on Spinal Fusion.吸烟对脊柱融合的影响。
Int J Spine Surg. 2017 Nov 28;11(4):29. doi: 10.14444/4029. eCollection 2017.
4
The Effect of Ketorolac on Thoracolumbar Posterolateral Fusion: A Systematic Review and Meta-Analysis.酮咯酸对胸腰椎后外侧融合术的影响:一项系统评价和荟萃分析。
Clin Spine Surg. 2018 Mar;31(2):65-72. doi: 10.1097/BSD.0000000000000613.
5
A meta-analysis comparing ALIF, PLIF, TLIF and LLIF.一项比较前路腰椎椎间融合术(ALIF)、后路腰椎椎间融合术(PLIF)、经椎间孔腰椎椎间融合术(TLIF)和斜外侧腰椎椎间融合术(LLIF)的荟萃分析。
J Clin Neurosci. 2017 Oct;44:11-17. doi: 10.1016/j.jocn.2017.06.013. Epub 2017 Jul 1.
6
The Role of Multimodal Analgesia in Spine Surgery.多模式镇痛在脊柱手术中的作用
J Am Acad Orthop Surg. 2017 Apr;25(4):260-268. doi: 10.5435/JAAOS-D-16-00049.
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Cortical Bone Trajectory Technique for Posterior Spinal Instrumentation.用于后路脊柱内固定的皮质骨轨迹技术
J Am Acad Orthop Surg. 2016 Nov;24(11):755-761. doi: 10.5435/JAAOS-D-15-00597.
8
Lumbar interbody fusion: techniques, indications and comparison of interbody fusion options including PLIF, TLIF, MI-TLIF, OLIF/ATP, LLIF and ALIF.腰椎椎间融合术:技术、适应证以及椎间融合选择的比较,包括后路腰椎椎间融合术(PLIF)、经椎间孔腰椎椎间融合术(TLIF)、改良经椎间孔腰椎椎间融合术(MI-TLIF)、斜外侧腰椎椎间融合术/前斜外侧腰椎椎间融合术(OLIF/ATP)、侧方腰椎椎间融合术(LLIF)和前路腰椎椎间融合术(ALIF)
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9
Effectiveness and safety of recombinant human bone morphogenetic protein-2 for adults with lumbar spine pseudarthrosis following spinal fusion surgery: A systematic review.重组人骨形态发生蛋白-2用于脊柱融合术后腰椎假关节形成成人患者的有效性和安全性:一项系统评价
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10
Laminectomy plus Fusion versus Laminectomy Alone for Lumbar Spondylolisthesis.后路腰椎滑脱症的椎板切除术联合融合术与单纯椎板切除术的比较。
N Engl J Med. 2016 Apr 14;374(15):1424-34. doi: 10.1056/NEJMoa1508788.

腰椎融合术失败及当前的治疗方式

Failure in Lumbar Spinal Fusion and Current Management Modalities.

作者信息

Cruz Alex, Ropper Alexander E, Xu David S, Bohl Michael, Reece Edward M, Winocour Sebastian J, Buchanan Edward, Kaung Geoffrey

机构信息

Department of Orthopaedic Surgery, Baylor College of Medicine, Houston, Texas.

Department of Neurosurgery, Baylor College of Medicine, Houston, Texas.

出版信息

Semin Plast Surg. 2021 Feb;35(1):54-62. doi: 10.1055/s-0041-1726102. Epub 2021 May 10.

DOI:10.1055/s-0041-1726102
PMID:33994880
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8110346/
Abstract

Lumbar spinal fusion is a commonly performed procedure to stabilize the spine, and the frequency with which this operation is performed is increasing. Multiple factors are involved in achieving successful arthrodesis. Systemic factors include patient medical comorbidities-such as rheumatoid arthritis and osteoporosis-and smoking status. Surgical site factors include choice of bone graft material, number of fusion levels, location of fusion bed, adequate preparation of fusion site, and biomechanical properties of the fusion construct. Rates of successful fusion can vary from 65 to 100%, depending on the aforementioned factors. Diagnosis of pseudoarthrosis is confirmed by imaging studies, often a combination of static and dynamic radiographs and computed tomography. Once pseudoarthrosis is identified, patient factors should be optimized whenever possible and a surgical plan implemented to provide the best chance of successful revision arthrodesis with the least amount of surgical risk.

摘要

腰椎融合术是一种常用的稳定脊柱的手术,且该手术的实施频率正在增加。实现成功的关节融合涉及多个因素。全身因素包括患者的内科合并症,如类风湿性关节炎和骨质疏松症,以及吸烟状况。手术部位因素包括骨移植材料的选择、融合节段的数量、融合床的位置、融合部位的充分准备以及融合结构的生物力学特性。根据上述因素,成功融合的比率在65%至100%之间变化。假关节的诊断通过影像学检查来确认,通常是静态和动态X线片以及计算机断层扫描的组合。一旦确定为假关节,应尽可能优化患者因素,并实施手术计划,以在手术风险最小的情况下提供成功翻修关节融合术的最佳机会。