Raiteb Mohamed, Elmrini Sanaa, Slimani Faiçal
Oral and Maxillofacial Surgery Department, CHU Ibn Rochd, B.P 2698, Casablanca, Morocco.
Faculty of Medicine and Pharmacy, Hassan II University of Casablanca, B.P 5696, Casablanca, Morocco.
Ann Med Surg (Lond). 2021 Apr 20;65:102296. doi: 10.1016/j.amsu.2021.102296. eCollection 2021 May.
Osteopetrosis is a rare genetic bone disease caused by a functional abnormality of the osteoclasts. Until now there is no codified management for the complications of this pathology and few cases cited in the literature.
a 19-year-old adult followed in our maxillofacial surgery department in the IBN ROCHD University Hospital for chronic osteomyelitis complicating mandibular osteopetrosis with skin fistulas. Patient operated several times. The persistence of osteomyelitis prevents the installation of a dental prosthesis and the appearance of new fistulas with continuous flow of pus alters the patient's quality of life.
Osteopetrosis is a group of rare genetic diseases characterized by osteoclastic insufficiency, poor bone remodeling and increased bone density. the benign form of osteopetrosis called Albers-Schönberg disease. It is a genetically inherited autosomal dominant disease.The large number of surgical interventions and the use of antibiotics for long periods of time (risk of development of resistance) significantly reduces the quality of life of patients. We must seek other measures to improve the prognosis and codify management.
In osteopetrosis, the maxillofacial surgeons should be aware about the early diagnosis and the appropriate management of the signs and prevent complications.
骨质石化症是一种由破骨细胞功能异常引起的罕见遗传性骨病。迄今为止，对于这种疾病的并发症尚无规范的治疗方法，且文献中引用的病例很少。
一名19岁成年人因慢性骨髓炎并发下颌骨骨质石化症伴皮肤瘘管，在伊本·罗什德大学医院颌面外科接受治疗。患者接受了多次手术。骨髓炎的持续存在妨碍了假牙的安装，新瘘管出现且持续有脓液流出，影响了患者的生活质量。
骨质石化症是一组罕见的遗传性疾病，其特征为破骨细胞功能不全、骨重塑不良和骨密度增加。骨质石化症的良性形式称为阿尔伯斯-尚伯格病。它是一种常染色体显性遗传疾病。大量的手术干预和长期使用抗生素（存在产生耐药性的风险）显著降低了患者的生活质量。我们必须寻求其他措施来改善预后并规范治疗方法。
在骨质石化症方面，颌面外科医生应意识到早期诊断以及对症状的适当处理，并预防并发症。
