Sun Lin, Wang Zhijun, Qin Shidi, Liang Chunhong, Zhao Ayong, He Ke
Key Laboratory of Applied Technology on Green-Eco-Healthy Animal Husbandry of Zhejiang Province, Hangzhou 311300, China.
Zhejiang Provincial Engineering Laboratory for Animal Health Inspection & Internet Technology, College of Animal Science and Technology & College of Veterinary Medicine, Zhejiang Agriculture and Forestry University, Hangzhou 311300, China.
Animals (Basel). 2025 Apr 29;15(9):1262. doi: 10.3390/ani15091262.
Antibiotic resistance has become a global health concern, driving the need for sustainable alternatives in animal husbandry. This study explores the potential of natural feed additives as a viable solution to enhance poultry growth and health while reducing reliance on antibiotics. Chinese herbal medicines and probiotics have been widely studied as green, healthy, and safe antibiotic alternatives in livestock and poultry production. A total of 120 chickens were randomly divided into four groups: a control group and three treatment groups supplemented with 1% powder, 3% fresh , or 1% . The results showed that powder significantly increased gamma-glutamylcysteine ( < 0.05), UDP-N-acetylglucosamine ( < 0.05), tyramine ( < 0.01), and leucine ( < 0.05). notably altered cecal metabolites, including L-tyrosine ( < 0.05), α-ketoisovaleric acid ( < 0.01), myristoleic acid ( < 0.01), glutathione ( < 0.05), and PGA1 ( < 0.05). modified cecal metabolites such as L-glutamine ( < 0.05), riboflavin ( < 0.05), L-Carnitine ( < 0.05), ergocalciferol ( < 0.01), and α-tocotrienol ( < 0.05).
抗生素耐药性已成为全球健康问题，促使畜牧业需要可持续的替代方案。本研究探讨了天然饲料添加剂作为一种可行解决方案的潜力，以促进家禽生长和健康，同时减少对抗生素的依赖。中草药和益生菌作为畜禽生产中绿色、健康、安全的抗生素替代品已得到广泛研究。总共120只鸡被随机分为四组：一个对照组和三个分别添加1%粉末、3%新鲜[物质名称未给出]或1%[物质名称未给出]的处理组。结果表明，[物质名称未给出]粉末显著增加了γ-谷氨酰半胱氨酸（P<0.05）、UDP-N-乙酰葡糖胺（P<0.05）、酪胺（P<0.01）和亮氨酸（P<0.05）。[物质名称未给出]显著改变了盲肠代谢物，包括L-酪氨酸（P<0.05）、α-酮异戊酸（P<0.01）、肉豆蔻油酸（P<0.01）、谷胱甘肽（P<0.05）和PGA1（P<0.05）。[物质名称未给出]改变了盲肠代谢物，如L-谷氨酰胺（P<0.05）、核黄素（P<0.05）、L-肉碱（P<0.05）、麦角钙化醇（P<0.01）和α-生育三烯酚（P<0.05）。
