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膳食添加剂益生菌对肠道微生物群的调节作用。

Dietary Additive Probiotics Modulation of the Intestinal Microbiota.

作者信息

Hu Shenglan, Wang Li, Jiang Zongyong

机构信息

Institute of Animal Science, Guangdong Academy of Agricultural Sciences, Guangzhou, Guangdong. China.

Institute of Animal Science, Guangdong Academy of Agricultural Sciences, Guangzhou 510640. China.

出版信息

Protein Pept Lett. 2017;24(5):382-387. doi: 10.2174/0929866524666170223143615.

Abstract

The importance of the intestinal microbiota of animals is widely acknowledged because of its vital role in the health of animals. There are complex communities of microbiota, which colonize the gastrointestinal tract. Intestinal microbiota are conductive to animal health and the development of the host immune system. Probiotics are commonly used dietary additives where they provide the host with many beneficial functions, such as modulating intestinal homeostasis and promoting gut health. These beneficial effects of probiotics may accrue from the inhibiting the growth of pathogenic bacteria and promoting the growth of beneficial flora in the gastrointestinal tract. Probiotics colonization and its impact on gut microbiota members are highly species specific. Different probiotics have been shown to have dramatically different capacities of modulation physiological function. This review summarizes existing studies of the influence of dietary additive probiotics on the gut microbiota in different animals, such as humans, mice, pigs and chickens, to clarify the contribution of different kinds of probiotics to the intestinal microbiota. Moreover, the probable mechanism for the benefits of dietary supplementation with probiotics will be discussed.

摘要

动物肠道微生物群的重要性因其在动物健康中的关键作用而得到广泛认可。存在复杂的微生物群落,它们定殖于胃肠道。肠道微生物群有助于动物健康和宿主免疫系统的发育。益生菌是常用的膳食添加剂,它们为宿主提供许多有益功能,如调节肠道内环境稳定和促进肠道健康。益生菌的这些有益作用可能源于抑制胃肠道中病原菌的生长以及促进有益菌群的生长。益生菌的定殖及其对肠道微生物群成员的影响具有高度的物种特异性。已表明不同的益生菌具有显著不同的调节生理功能的能力。本综述总结了现有关于膳食添加剂益生菌对不同动物(如人类、小鼠、猪和鸡)肠道微生物群影响的研究,以阐明不同种类益生菌对肠道微生物群的贡献。此外,还将讨论膳食补充益生菌产生益处的可能机制。

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