Berz Annuska, Pasquini de Souza Camila, Wöhr Markus, Schwarting Rainer K W
Behavioral Neuroscience, Experimental and Biological Psychology, Faculty of Psychology, Philipps-University Marburg, Gutenberg-Straße 18, 35032 Marburg, Germany.
Center for Mind, Brain and Behavior, Philipps-University Marburg, Hans-Meerwein-Straße 6, 35032 Marburg, Germany.
iScience. 2021 Apr 20;24(5):102426. doi: 10.1016/j.isci.2021.102426. eCollection 2021 May 21.
Communication constitutes a fundamental component of mammalian social behavior. Rats are highly social animals and emit 50-kHz ultrasonic vocalizations (USV), which function as social contact calls. Playback of 50-kHz USV leads to strong and immediate social approach responses in receiver rats, but this response is weak or even absent during repeated 50-kHz USV playback. Given the important role of 50-kHz USV in initiating social contact and coordinating social interactions, the occurrence of habituation is highly unexpected. It is not clear why a social signal characterized by significant incentive salience loses its power to change the behavior of the receiver so rapidly. Here, we show that the habituation phenomenon displayed by rats in response to repeated playback of 50-kHz USV (1) is characterized by limited generalizability because it is present in Wistar but not Sprague-Dawley rats, (2) can be overcome by amphetamine treatment, and (3) depends on the subject's internal state.
交流是哺乳动物社会行为的一个基本组成部分。大鼠是高度群居的动物，会发出50千赫兹的超声波发声（USV），其作用是作为社会联系叫声。回放50千赫兹的USV会在接收大鼠中引发强烈且即时的社会接近反应，但在重复回放50千赫兹的USV时，这种反应会减弱甚至消失。鉴于50千赫兹的USV在启动社会接触和协调社会互动方面的重要作用，习惯化的出现是非常出乎意料的。目前尚不清楚为什么一个具有显著激励显著性的社会信号会如此迅速地失去改变接收者行为的能力。在这里，我们表明，大鼠对50千赫兹USV重复回放所表现出的习惯化现象：（1）具有有限的普遍性，因为它在Wistar大鼠中存在，而在Sprague-Dawley大鼠中不存在；（2）可以通过苯丙胺治疗克服；（3）取决于受试者的内部状态。
