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反复出现可触及的游走性弓形红斑,与 IVIg 输注有关。

Recurrent episodes of palpable migratory arciform erythema associated with IVIg infusions.

机构信息

Section of Dermatology, Department of Internal Medicine, Virginia Tech Carilion School of Medicine and Carilion Clinic, Roanoke, VA.

出版信息

Dermatol Online J. 2021 Apr 15;27(4):13030/qt7xg2k983.

PMID:33999580
Abstract

Palpable migratory arciform erythema (PMAE) is an uncommon T cell pseudolymphoma characterized by erythematous, annular-to-arciform papules and plaques. Although the eruption is self-limited in most cases, recurrences are routine. Diagnosis requires attention to clinical history as well as histopathologic analysis, which allow for differentiation from other T cell pseudolymphomas and gyrate erythemas. A common triggering factor has not been identified. We report a 60-year-old man who developed PMAE after IVIg infusion. Interestingly, although the individual eruptions were self-limited and resolved after several weeks, subsequent infusions predictably resulted in recurrence of PMAE, confirming the association. To our knowledge, this is the first reported case of recurrent PMAE in association with IVIg infusions.

摘要

可触及游走性弓形红斑(PMAE)是一种罕见的 T 细胞假性淋巴瘤,其特征为红斑、环形至弓形丘疹和斑块。尽管大多数情况下皮疹是自限性的,但会经常复发。诊断需要注意临床病史和组织病理学分析,以便与其他 T 细胞假性淋巴瘤和回旋状红斑相区分。尚未确定常见的触发因素。我们报告了 1 例 60 岁男性,在静脉注射免疫球蛋白(IVIg)输注后出现 PMAE。有趣的是,尽管每次皮疹都是自限性的,并在数周后自行消退,但随后的输注可预测地导致 PMAE 复发,证实了两者的相关性。据我们所知,这是首例与 IVIg 输注相关的复发性 PMAE 报道。

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