血小板与淋巴细胞比值和 C 反应蛋白作为结直肠息肉组织学分型的标志物。
Platelet-to-lymphocyte ratio and C-reactive protein as markers for colorectal polyp histological type.
机构信息
Department of Gastroenterology, Shandong Provincial Hospital Affiliated to Shandong First Medical University & Shandong Academy of Medical Sciences, 324 Jingwu Road, Jinan, 250021, Shandong, People's Republic of China.
Department of Oncology, Shandong Provincial Hospital Affiliated to Shandong First Medical University & Shandong Academy of Medical Sciences, Jinan, Shandong, China.
出版信息
BMC Cancer. 2021 May 17;21(1):556. doi: 10.1186/s12885-021-08221-9.
BACKGROUND
The platelet-to-lymphocyte ratio (PLR) and C-reactive protein (CRP) level are markers that have been reported to predict the histological type of various tumors, and here, we evaluated their utility in predicting colorectal polyp histological types.
METHODS
We retrospectively reviewed 172 patients with colorectal polyps who underwent endoscopic polypectomy. The associations between histological type and clinicopathologic parameters were assessed by multivariate analysis.
RESULTS
The optimal PLR and CRP cut-off values were 113.32 and 0.39, respectively. The PLR (P = 0.002) and CRP (P = 0.009) values were associated with the histological type according to the univariate analysis, whereas low PLR (P ≤ 0.001) and CRP (P = 0.017) values were independent risk factors in the multivariate analysis together with maximum tumor diameter (P ≤ 0.001) and tumor number (P = 0.0014).
CONCLUSIONS
Preoperative PLR and CRP are correlated with the colorectal polyp histological type.
背景
血小板与淋巴细胞比值（PLR）和 C 反应蛋白（CRP）水平已被报道可预测各种肿瘤的组织学类型，在此，我们评估其在预测结直肠息肉组织学类型中的作用。
方法
我们回顾性分析了 172 例接受内镜息肉切除术的结直肠息肉患者。通过多因素分析评估组织学类型与临床病理参数之间的相关性。
结果
最佳 PLR 和 CRP 截断值分别为 113.32 和 0.39。根据单因素分析，PLR（P=0.002）和 CRP（P=0.009）值与组织学类型相关，而低 PLR（P≤0.001）和 CRP（P=0.017）值是最大肿瘤直径（P≤0.001）和肿瘤数量（P=0.0014）的独立危险因素。
结论
术前 PLR 和 CRP 与结直肠息肉的组织学类型相关。
Zotero 插件