Hirano M, Hibi S, Yoshida T, Hirade Y, Kasuya H, Kikuchi Y
Department of Otolaryngology-Head and Neck Surgery, Kurume University, Japan.
Acta Otolaryngol. 1988 May-Jun;105(5-6):432-8. doi: 10.3109/00016488809119497.
Tape-recorded voices of 30 patients were acoustically analysed: 10 had glottic Tla carcinoma, 10 unilateral vocal fold polyp and 10 unilateral recurrent laryngeal nerve paralysis. The carcinoma cases were treated with laser surgery with/without radiotherapy, the polyp cases with endolaryngeal microsurgery and the paralysis cases with intrafold silicone injection. The acoustic analysis was conducted before and after the treatment for each patient. Three acoustic parameters, viz. pitch perturbation quotient (PPQ), amplitude perturbation quotient (APQ) and normalized noise energy (NNE), were employed. The results were as follows: (1) PPQ and APQ were greater in paralysis cases than in carcinoma and polyp cases; (2) none of the parameters was useful in differentiating the three disease groups investigated; (3) all three parameters proved to be useful in monitoring the effects of treatments; (4) all three parameters were positively correlated to the grade of hoarseness, rough and breathy quality of hoarseness, mean airflow rate and regularity of vocal fold vibration viewed under stroboscopy; (5) PPQ, APQ and NNE were positively related to each other.
对30名患者的录音进行了声学分析：其中10例患有声门Tla癌，10例单侧声带息肉，10例单侧喉返神经麻痹。癌病例采用激光手术联合或不联合放疗治疗，息肉病例采用喉内显微手术治疗，麻痹病例采用声带内注射硅胶治疗。对每位患者在治疗前后进行声学分析。采用了三个声学参数，即基频微扰商（PPQ）、振幅微扰商（APQ）和归一化噪声能量（NNE）。结果如下：（1）麻痹病例的PPQ和APQ高于癌和息肉病例；（2）没有一个参数有助于区分所研究的三个疾病组；（3）所有三个参数都被证明对监测治疗效果有用；（4）所有三个参数与嘶哑程度、嘶哑的粗糙和呼吸音质、平均气流率以及频闪喉镜下观察到的声带振动规律性呈正相关；（5）PPQ、APQ和NNE彼此呈正相关。
