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分体骨块技术:一项随机临床试验的 4 个月结果,比较自体和异种皮质板的临床和影像学结果。

Split bone block technique: 4-month results of a randomised clinical trial comparing clinical and radiographic outcomes between autogenous and xenogeneic cortical plates.

出版信息

Int J Oral Implantol (Berl). 2021 Mar 16;14(1):41-52.

Abstract

PURPOSE

To evaluate short-term clinical and radiographic outcomes of bone regeneration procedures using thin cortical porcine xenogeneic bone plates in combination with autogenous bone chips compared with thin autogenous cortical plates and autogenous bone chips.

MATERIALS AND METHODS

A total of 19 patients (12 women and 7 men, mean age 58.24 ± 3.09 years) were randomly allocated to two different groups regarding surgical procedure: autogenous cortical plates (ACP group) and xenogeneic cortical plates (XCP group). Preoperative CBCT scans were performed for each patient. Surgical time and postoperative pain were recorded, as well as tissue healing and graft resorption after 4 months, then another surgical procedure was performed to place dental implants. Data were analysed using an analysis of covariance.

RESULTS

Twenty-one surgical procedures were performed on 19 patients (10 from the XCP group and 9 from the ACP group). The operative time was significantly lower in the XCP group (25.45 ± 3.88 minutes) than in the ACP group (44.10 ± 3.60 minutes). The XCP group also showed less pain, but not significantly less, than the ACP group. The graft resorption rate in the ACP and XCP groups was 2.03 ± 1.58% and 3.49 ± 2.38% respectively, showing no statistically significant difference.

CONCLUSIONS

Despite the limited sample size and non-uniform distribution between the maxilla and mandible as surgical sites, the results suggest that XCP and ACP grafts are similar in terms of bone volume gain and graft resorption rate, with no significant differences in wound healing or complication rate. Nevertheless, the XCP group recorded lower pain levels and required significantly less operative time compared to the ACP group.

摘要

目的

评估使用薄皮质猪异种骨板联合自体骨屑与薄自体皮质板和自体骨屑联合进行骨再生手术的短期临床和影像学结果。

材料和方法

共有 19 名患者(12 名女性和 7 名男性,平均年龄 58.24 ± 3.09 岁)被随机分为两组,分别采用不同的手术方法:自体皮质板(ACP 组)和异种皮质板(XCP 组)。对每位患者进行术前 CBCT 扫描。记录手术时间和术后疼痛,以及 4 个月后组织愈合和移植物吸收情况,然后再进行另一次手术放置牙种植体。数据采用协方差分析进行分析。

结果

19 名患者共进行了 21 次手术(XCP 组 10 例,ACP 组 9 例)。XCP 组的手术时间明显低于 ACP 组(25.45 ± 3.88 分钟比 44.10 ± 3.60 分钟)。XCP 组的疼痛也比 ACP 组小,但无统计学意义。ACP 组和 XCP 组的移植物吸收率分别为 2.03 ± 1.58%和 3.49 ± 2.38%,无统计学差异。

结论

尽管样本量有限,上颌和下颌作为手术部位的分布不均匀,但结果表明,XCP 和 ACP 移植物在骨量增加和移植物吸收率方面相似,在伤口愈合或并发症发生率方面无显著差异。然而,与 ACP 组相比,XCP 组的疼痛水平较低,手术时间明显缩短。

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