Christensen Jeppe Gronemann, Grønlund Gustav Pors, Georgi Signe Risom, Starch-Jensen Thomas, Bruun Niels Henrik, Jensen Simon Storgård
Research Area Oral Surgery, Section for Oral Biology and Immunopathology, Department of Odontology, Faculty of Health and Medical Sciences, University of Copenhagen, CopenhagenDenmark.
All authors contributed equally to the present study.
J Oral Maxillofac Res. 2023 Jun 30;14(2):e1. doi: 10.5037/jomr.2023.14201. eCollection 2023 Apr-Jun.
The objective of the present systematic review and meta-analysis was to test the 0-hypothesis of no difference in implant treatment outcome after horizontal alveolar ridge augmentation with xenogenic block compared with autogenous bone block.
A literature search was conducted using PubMed, Embase and Cochrane Library databases in combination with a hand-search of relevant journals until 25 of January 2022. Comparative and non-comparative studies evaluating horizontal alveolar ridge augmentations with xenogenic blocks were included. Quality and risk of bias were evaluated by Cochrane Collaboration's revised tool and Newcastle-Ottawa scale.
Meta-analysis revealed no statistically significant difference in implant survival rate after more than 6 months of functional implant loading (P = 0.71), no difference in alveolar ridge width (P = 0.07) or gain of alveolar ridge width at re-entry (P = 0.13). Non-comparative studies revealed moderate to high short-term implant survival rate and gain in alveolar ridge width, however, complications including dehiscences, graft exposure and graft failure were observed in several studies.
No significant difference could be identified in short-term implant treatment outcome following horizontal alveolar ridge augmentation using xenogenic block compared with autogenous bone block with the limited data available. A high incidence of healing complications and implant failures necessitates further investigation, as well as long-term results on implant survival rate.
本系统评价和荟萃分析的目的是检验以下零假设:与自体骨块相比,使用异种骨块进行水平牙槽嵴增高术后种植治疗结果无差异。
使用PubMed、Embase和Cochrane图书馆数据库进行文献检索,并结合对相关期刊的手工检索,直至2022年1月25日。纳入评估使用异种骨块进行水平牙槽嵴增高的比较性和非比较性研究。采用Cochrane协作组修订工具和纽卡斯尔-渥太华量表评估质量和偏倚风险。
荟萃分析显示,在功能性种植体加载6个月以上后,种植体存活率无统计学显著差异(P = 0.71),牙槽嵴宽度无差异(P = 0.07),再次切开时牙槽嵴宽度增加无差异(P = 0.13)。非比较性研究显示短期种植体存活率和牙槽嵴宽度增加为中度至高度,然而,在几项研究中观察到包括裂开、植骨暴露和植骨失败在内的并发症。
根据现有有限数据,与自体骨块相比,使用异种骨块进行水平牙槽嵴增高术后的短期种植治疗结果无显著差异。愈合并发症和种植体失败的高发生率需要进一步研究,以及种植体存活率的长期结果。