Unit of Biostatistics and Research Methodology, School of Medical Sciences, Universiti Sains Malaysia - Kampus Kesihatan, Kubang Kerian, Malaysia.
Unit of Biostatistics and Research Methodology, School of Medical Sciences, Universiti Sains Malaysia - Kampus Kesihatan, Kubang Kerian, Malaysia
BMJ Open. 2021 May 18;11(5):e043642. doi: 10.1136/bmjopen-2020-043642.
Estimation of the net survival of breast cancer helps in assessing breast cancer burden at a population level. Thus, this study aims to estimate the net survival of breast cancer at different cancer staging and age at diagnosis in the east coast region of West Malaysia.
Kelantan, Malaysia.
All breast cancer cases diagnosed in 2007 and 2011 identified from Kelantan Cancer Registry.
This retrospective cohort study used a relative survival approach to estimate the net survival of patients with breast cancer. Thus, two data were needed; breast cancer data from Kelantan Cancer Registry and general population mortality data for Kelantan population.
Net survival according to stage and age group at diagnosis at 1, 3 and 5 years following diagnosis.
The highest net survival was observed among stage I and II breast cancer cases, while the lowest net survival was observed among stage IV breast cancer cases. In term of age at diagnosis, breast cancer cases aged 65 and older had the best net survival compared with the other age groups.
The age at diagnosis had a minimal impact on the net survival compared with the stage at diagnosis. The finding of this study is applicable to other populations with similar breast cancer profile.
乳腺癌的净生存率估计有助于评估人群水平的乳腺癌负担。因此，本研究旨在估计马来西亚西海岸东海岸地区不同癌症分期和诊断时年龄的乳腺癌净生存率。
马来西亚吉兰丹。
从吉兰丹癌症登记处确定的 2007 年和 2011 年诊断的所有乳腺癌病例。
本回顾性队列研究使用相对生存率方法估计乳腺癌患者的净生存率。因此，需要两种数据；吉兰丹癌症登记处的乳腺癌数据和吉兰丹人口的一般人群死亡率数据。
诊断后 1、3 和 5 年的分期和诊断时年龄组的净生存率。
I 期和 II 期乳腺癌病例的净生存率最高，而 IV 期乳腺癌病例的净生存率最低。就诊断时的年龄而言，65 岁及以上的乳腺癌病例的净生存率与其他年龄组相比最好。
与诊断时的分期相比，诊断时的年龄对净生存率的影响最小。本研究的结果适用于具有类似乳腺癌特征的其他人群。
