Fujinaga Atsuro, Hirashita Teijiro, Endo Yuichi, Itai Yusuke, Kawamura Masahiro, Nakanuma Hiroaki, Watanabe Kiminori, Kawasaki Takahide, Masuda Takashi, Ohta Masayuki, Inomata Masafumi
Dept. of Gastroenterological and Pediatric Surgery, Oita University Faculty of Medicine.
Gan To Kagaku Ryoho. 2021 May;48(5):689-691.
Some reports have shown that the prognosis of recurrent lung metastases after resection of pancreatic cancer is better than that for other organs. We report on 2 cases of long‒term survival after lung resection for lung metastases from pancreatic cancer. Case 1: A 73‒year‒old man underwent distal pancreatectomy for pancreatic body cancer. Adjuvant chemotherapy of S‒1 was administered for 6 months. At 3 years after surgery, 2 small metastatic nodules were detected in the right lung, and the patient underwent thoracoscopic right upper lobectomy. At 5 years and 9 months after the initial surgery, he is alive without recurrence. Case 2: An 81‒year‒old woman underwent pylorus‒preserving pancreatoduodenectomy for pancreatic head cancer. Adjuvant chemotherapy of S‒1 was administered for 4 months. At 1 year and 9 months after surgery, a metastatic nodule was detected in the left upper lung, and the patient underwent thoracoscopic left upper lobectomy. At 4 years and 6 months after initial surgery, radiation therapy was performed for localized bone metastasis. At 5 years and 1 month after the initial surgery, she is alive without other recurrences. In conclusion, recurrent lung metastases of pancreatic cancer with a small number of metastases may result in long‒term survival following resection.
一些报告显示，胰腺癌切除术后肺转移复发的预后优于其他器官。我们报告2例因胰腺癌肺转移行肺切除术后长期生存的病例。病例1：一名73岁男性因胰体癌接受了胰体尾切除术。给予S-1辅助化疗6个月。术后3年，右肺发现2个小转移结节，患者接受了胸腔镜右上叶切除术。初次手术后5年9个月，他仍存活且无复发。病例2：一名81岁女性因胰头癌接受了保留幽门的胰十二指肠切除术。给予S-1辅助化疗4个月。术后1年9个月，左上肺发现一个转移结节，患者接受了胸腔镜左上叶切除术。初次手术后4年6个月，因局部骨转移进行了放射治疗。初次手术后5年1个月，她仍存活且无其他复发。总之，胰腺癌肺转移复发且转移灶数量少的患者，切除术后可能实现长期生存。
