Sakimura Chie, Hori Takeshi, Deguchi Sota, Masuda Go, Tendo Masashige, Nakata Bunzo, Ishikawa Tetsuro, Hirakawa Kosei
Dept. of Surgery, Kashiwara Municipal Hospital.
Gan To Kagaku Ryoho. 2019 Dec;46(13):1934-1936.
A 66-year-old man had an elevated CEA level. Further examinations showed a pancreatic head tumor. A pancreaticoduodenectomy was then performed. The histopathological examination showed a mixed tumor of papillary adenocarcinoma and neuroendocrine cancer. In addition, a tumor in the upper lobe of the right lung was found 18 months after the initial pancreatic resection, and the bronchoscope indicated lung metastasis. The patient underwent partial pneumonectomy. After the pneumonectomy, he received S-1 chemotherapy. Thirty -nine months after the pneumonectomy, CEA was slightly elevated. We changed the chemotherapy to gemcitabine and nab-paclitaxel without further examinations to confirm the recurrence. The patient discontinued chemotherapy after CEA fell within the normal range. He has been alive without tumor relapse for 64 months since the second operation for the lung metastasis. We report a successful case of lung resection for lung metasta- sis from pancreatic cancer.
一名66岁男性癌胚抗原(CEA)水平升高。进一步检查发现胰头肿瘤。随后进行了胰十二指肠切除术。组织病理学检查显示为乳头状腺癌和神经内分泌癌的混合肿瘤。此外,在初次胰腺切除术后18个月,发现右肺上叶有肿瘤,支气管镜检查提示肺转移。患者接受了肺部分切除术。肺切除术后,他接受了S-1化疗。肺切除术后39个月,CEA略有升高。我们在未进一步检查确认复发的情况下,将化疗方案改为吉西他滨和纳米白蛋白结合型紫杉醇。CEA降至正常范围后,患者停止化疗。自第二次因肺转移进行手术后,他已无肿瘤复发存活64个月。我们报告了一例成功切除胰腺癌肺转移灶的病例。