Zinzuwadia Shuchi, Olivieri John, Zhang Cheryl, Ananthanarayanan Vijayalakshmi, Freiburg Luke, Allam Emad
Loyola University Medical Center, Department of Radiology, 2160 S 1st Ave, Maywood, IL 60153 USA.
Radiol Case Rep. 2021 Apr 30;16(7):1718-1726. doi: 10.1016/j.radcr.2021.03.056. eCollection 2021 Jul.
Differentiation of primary versus secondary breast cancer can be difficult, with the relative rarity of the latter representing a diagnostic challenge. Here, we present a case of small cell lung cancer with synchronous bilateral breast metastases in a 52-year-old female. There are less than 5 other cases of small cell lung cancer with bilateral breast metastases reported in the literature to date. The breast metastases represented the first clinical and imaging manifestation of malignancy in our case. We present the patient's disease course including multi-modal imaging, histopathologic analysis, and clinical management. We aim to highlight the entity of secondary breast cancer and how multidisciplinary collaboration can help arrive at the diagnosis, which is critical for prognosis and treatment planning in this patient population.
原发性乳腺癌与继发性乳腺癌的鉴别可能具有挑战性,后者相对罕见,这构成了诊断难题。在此,我们报告一例52岁女性小细胞肺癌伴双侧乳腺同步转移的病例。迄今为止,文献报道的小细胞肺癌伴双侧乳腺转移的病例不足5例。在我们的病例中,乳腺转移是恶性肿瘤的首个临床和影像学表现。我们展示了患者的病程,包括多模态影像学检查、组织病理学分析及临床管理。我们旨在强调继发性乳腺癌这一实体,以及多学科协作如何有助于做出诊断,这对于该患者群体的预后和治疗规划至关重要。