Internal Medicine Department, Faculty of Medicine, Cairo University, Giza, Egypt.
General Surgery Department, Faculty of Medicine, Cairo University, Giza, Egypt.
Ann Med. 2021 Dec;53(1):523-530. doi: 10.1080/07853890.2021.1903072.
Epicardial fat thickness is an interesting parameter of early atherosclerosis. We prospectively assessed whether weight loss following laparoscopic sleeve gastrectomy (LSG) leads to a significant reduction in the epicardial fat thickness (EFT) and the correlation between the decline in the epicardial fat thickness with other clinical parameters.
A prospective analysis of 98 cases that were scheduled to undergo LSG and followed up for 12 months was conducted. EFT was assessed using two-dimensional (2 D) echocardiography.
A total of 98 cases and 70 controls were enrolled. EFT demonstrated a significant reduction at follow-up in the whole group (median 8.9 (1.95) versus 7.65 (1.67) mm, respectively). The degree of reduction was higher in the LSG cohort compared to control cohort 1.3 (0.4) versus 1 (0.4), respectively; < .001). The univariate regression analysis demonstrated a notable correlation of the EFT with the weight, body mass index (BMI), fasting blood glucose (FBG), and creatinine with a -value of <.0001, .001, .022, and .018, respectively while the multivariate analysis showed a strong correlation between EFT and weight and creatinine with a -value of <.0001 and .033 respectively.
LSG can have a favourable impact on metabolic syndrome aspects, namely EFT, as it can decrease it considerably.
心外膜脂肪厚度是动脉粥样硬化早期的一个有趣参数。我们前瞻性评估了腹腔镜袖状胃切除术（LSG）后体重减轻是否会导致心外膜脂肪厚度（EFT）显著减少，以及 EFT 下降与其他临床参数之间的相关性。
对 98 例行 LSG 并随访 12 个月的病例进行前瞻性分析。使用二维（2D）超声心动图评估 EFT。
共纳入 98 例病例和 70 例对照。全组 EFT 在随访时显著降低（中位数 8.9（1.95）比 7.65（1.67）mm）。LSG 组比对照组的降低程度更高，分别为 1.3（0.4）比 1（0.4）；<0.001）。单因素回归分析显示，EFT 与体重、体重指数（BMI）、空腹血糖（FBG）和肌酐显著相关，值分别为<0.0001、0.001、0.022 和 0.018；而多元分析显示，EFT 与体重和肌酐之间存在很强的相关性，值分别为<0.0001 和 0.033。
LSG 可以对代谢综合征方面产生有利影响，即 EFT，因为它可以显著降低 EFT。
