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减重与代谢手术后心外膜脂肪组织的变化:系统评价和荟萃分析。

Epicardial Adipose Tissue Changes After Bariatric and Metabolic Surgery: a Systematic Review and Meta-analysis.

机构信息

Faculty of Medicine, Universidad Complutense de Madrid, Madrid, Spain.

Faculty of Medicine, Università la Sapienza di Roma, Rome, Italy.

出版信息

Obes Surg. 2023 Nov;33(11):3636-3648. doi: 10.1007/s11695-023-06848-0. Epub 2023 Oct 6.

DOI:10.1007/s11695-023-06848-0
PMID:37801237
Abstract

Epicardial adipose tissue (EAT) is a visceral fat depot located between the myocardium and visceral epicardium. Emerging evidence suggests that excessive EAT is linked to increased risk of cardiovascular conditions and other metabolic diseases. A literature search was conducted from the earliest studies to the 26th of November 2022 on PubMed, Embase, and the Cochrane. All the studies evaluating changes in EAT, pericardial adipose tissue (PAT), or total cardiac fat loss before and after BS were included. From 623 articles, 35 were eventually included in the systematic review. Twenty-one studies showed a significant reduction of EAT after BS, and only one study showed a non-significant reduction (p = 0.2).

摘要

心外膜脂肪组织(EAT)是一种位于心肌和内脏心外膜之间的内脏脂肪库。新出现的证据表明,过多的心外膜脂肪组织与心血管疾病和其他代谢性疾病风险增加有关。对 PubMed、Embase 和 Cochrane 进行了从最早的研究到 2022 年 11 月 26 日的文献检索。所有评估 BS 前后 EAT、心包脂肪组织(PAT)或总心脏脂肪损失变化的研究均包括在内。从 623 篇文章中,最终有 35 篇被纳入系统评价。21 项研究显示 BS 后 EAT 显著减少,只有一项研究显示 EAT 减少无统计学意义(p = 0.2)。

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