Rodrigo M R, Rosenquist J B
Department of Oral Surgery and Oral Medicine, Faculty of Dentistry, University of Hong Kong, Prince Philip Dental Hospital.
Anaesthesia. 1988 May;43(5):369-75. doi: 10.1111/j.1365-2044.1988.tb09015.x.
Isoflurane 0.5% in oxygen for conscious sedation was compared with placebo (oxygen) and with an equipotent concentration of nitrous oxide in oxygen, in patients scheduled for surgical removal of bilateral, similarly impacted lower third molars. The majority of patients were sedated with 0.5% isoflurane in oxygen and preferred it to both placebo and nitrous oxide in oxygen. It produced good operating conditions with cooperative patients and had no significant effect on vital signs. There were no significant intra- or postoperative adverse effects. Patients were street fit within 10 minutes after the end of the operation.
在计划手术拔除双侧、情况相似的低位阻生下颌第三磨牙的患者中，将0.5%异氟烷与氧气混合用于清醒镇静，与安慰剂（氧气）以及与氧气混合的等效浓度一氧化二氮进行比较。大多数患者使用0.5%异氟烷与氧气混合进行镇静，相较于安慰剂和与氧气混合的一氧化二氮，他们更喜欢这种方式。它为配合良好的患者创造了良好的手术条件，且对生命体征无显著影响。术中及术后均无显著不良反应。患者在手术结束后10分钟内即可恢复正常活动。
