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Neuromelanin-Sensitive Magnetic Resonance Imaging as a Proxy Marker for Catecholamine Function in Psychiatry.

作者信息

Horga Guillermo, Wengler Kenneth, Cassidy Clifford M

机构信息

Department of Psychiatry, Columbia University, New York, New York.

Division of Translational Imaging, New York State Psychiatric Institute, New York.

出版信息

JAMA Psychiatry. 2021 Jul 1;78(7):788-789. doi: 10.1001/jamapsychiatry.2021.0927.

DOI:10.1001/jamapsychiatry.2021.0927
PMID:34009285
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9060608/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ed9/9060608/50db8e91669c/nihms-1800706-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ed9/9060608/50db8e91669c/nihms-1800706-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5ed9/9060608/50db8e91669c/nihms-1800706-f0001.jpg

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Neuropsychopharmacology. 2021 Jun;46(7):1233-1239. doi: 10.1038/s41386-020-00860-z. Epub 2020 Sep 12.
3
Multimodal dopamine transporter (DAT) imaging and magnetic resonance imaging (MRI) to characterise early Parkinson's disease.
神经黑色素磁共振成像确定蓝斑和黑质变性是孤立性快速眼动睡眠行为障碍的关键鉴别因素。
Brain Imaging Behav. 2025 Feb;19(1):72-81. doi: 10.1007/s11682-024-00926-2. Epub 2024 Oct 30.
4
Neuromelanin-sensitive MRI for mechanistic research and biomarker development in psychiatry.神经黑色素敏感 MRI 在精神病学中的机制研究和生物标志物开发中的应用。
Neuropsychopharmacology. 2024 Nov;50(1):137-152. doi: 10.1038/s41386-024-01934-y. Epub 2024 Aug 19.
5
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多模态多巴胺转运体（DAT）成像与磁共振成像（MRI）用于早期帕金森病的特征描述。
Parkinsonism Relat Disord. 2020 Oct;79:26-33. doi: 10.1016/j.parkreldis.2020.08.010. Epub 2020 Aug 17.
4
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Neuromelanin-sensitive MRI as a noninvasive proxy measure of dopamine function in the human brain.神经黑色素敏感 MRI 作为一种非侵入性的人类大脑多巴胺功能替代测量指标。
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6
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7
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