Wicks I P, Moore J, Fleming A
Department of Rheumatology, Prince Henry Hospital, Sydney, Australia.
Ann Rheum Dis. 1988 Jul;47(7):563-9. doi: 10.1136/ard.47.7.563.
An analysis of mortality related to rheumatoid arthritis (RA) in Australia for the period 1950 to 1981 was undertaken based on information recorded in death certificates. These data include every death over a 32 year period where RA was considered to be the underlying cause. Death from RA was commonly reported (0.17% of all deaths). The mean age at death from RA in both sexes exceeded that of the general population for most of the period. There was little difference between patients dying of RA and the general population for age at death in the over 50 years' age group. There was a significant decrease in mortality for women dying of RA over the age of 75. RA accounted for more deaths in women than in men (in a ratio of 2.2:1). Men tended to die at a younger age from RA than did women. The impact of RA remained relatively constant in relation both to the total causes of death and to deaths due to other musculoskeletal diseases. There was a significant decline, however, in female RA deaths as a percentage of deaths due to all musculoskeletal diseases. Cohort analysis does not indicate any marked effect from extrinsic factors on mortality due to RA.
基于死亡证明记录的信息,对1950年至1981年期间澳大利亚类风湿性关节炎(RA)相关死亡率进行了分析。这些数据涵盖了32年期间所有将RA视为根本死因的死亡情况。RA导致的死亡常见(占所有死亡人数的0.17%)。在该时期的大部分时间里,因RA死亡的男女平均年龄均超过普通人群。在50岁以上年龄组中,死于RA的患者与普通人群在死亡年龄上差异不大。75岁以上死于RA的女性死亡率显著下降。RA导致的女性死亡人数多于男性(比例为2.2:1)。男性因RA死亡的年龄往往比女性小。RA对总死亡原因以及其他肌肉骨骼疾病导致的死亡的影响相对保持不变。然而,女性RA死亡占所有肌肉骨骼疾病导致死亡的百分比显著下降。队列分析未表明外部因素对RA相关死亡率有任何显著影响。