Satoh J, Miyasaka N, Yamada T, Nishido T, Okuda M, Kuroiwa T, Shimokawa R
First Department of Internal Medicine, Tokyo Medical and Dental University, Japan.
Ann Rheum Dis. 1988 Jul;47(7):606-11. doi: 10.1136/ard.47.7.606.
The central nervous system is often affected in Wegener's granulomatosis (WG), but massive cerebral infarction due to occlusion of branches of the anterior cerebral arteries (ACA) by granulomatous lesions or thrombosis, or both, has seldom been reported. A case is reported here of a 67 year old man with WG complicated by generalised necrotising vasculitis in the lung, kidney, and gastrointestinal tract, and cerebral infarction in the territory of both anterior cerebral arteries, probably caused by thrombosis and a contiguous invasion of granulomatous lesion from the nasal cavity.
韦格纳肉芽肿（WG）常累及中枢神经系统，但由肉芽肿性病变或血栓形成或两者共同导致大脑前动脉（ACA）分支闭塞引起的大面积脑梗死鲜有报道。本文报告一例67岁男性患者，患有WG，并发肺、肾和胃肠道的全身性坏死性血管炎，以及双侧大脑前动脉供血区的脑梗死，可能是由血栓形成以及鼻腔肉芽肿性病变的连续蔓延所致。
