Ellis T M, Robinson W F, Wilcox G E
Animal Health Laboratories, Department of Agriculture, South Perth, Western Australia.
Aust Vet J. 1988 Mar;65(3):69-73. doi: 10.1111/j.1751-0813.1988.tb07361.x.
Fifty dairy goats, of various ages, sexes and breeds were selected for examination on the basis of positive serological reactions to caprine arthritis-encephalitis virus (CAEV). Thirty-one had lung lesions including chronic interstitial pneumonia of caudal or cranioventral lobes, bronchopneumonia, verminous pneumonia, pulmonary cryptococcosis or combinations of these. The only infective agent recovered from all the chronic interstitial pneumonia cases examined was CAEV, which was also recovered from lung tissue of 3 goats with arthritis but no lung lesions. The presence of CAEV in lavaged alveolar macrophages from normal lung tissue and from lungs affected with chronic interstitial pneumonia and verminous pneumonia, and the demonstration of a marked increase in nonspecific esterase staining macrophages in areas of chronic interstitial pneumonia, are discussed in relation to the aetiology of the pneumonia.
根据对山羊关节炎-脑炎病毒（CAEV）血清学反应呈阳性，选取了50只不同年龄、性别和品种的奶山羊进行检查。其中31只存在肺部病变，包括尾叶或颅腹侧叶慢性间质性肺炎、支气管肺炎、寄生虫性肺炎、肺隐球菌病或这些病变的组合。在所有检查的慢性间质性肺炎病例中唯一分离出的感染因子是CAEV，在3只有关节炎但无肺部病变的山羊的肺组织中也分离出了CAEV。文中讨论了正常肺组织、慢性间质性肺炎和寄生虫性肺炎肺组织灌洗的肺泡巨噬细胞中CAEV的存在情况，以及慢性间质性肺炎区域非特异性酯酶染色巨噬细胞显著增加的情况，并探讨了其与肺炎病因的关系。
