Althemery Abdullah
Clinical Pharmacy Department, College of Pharmacy, Prince Sattam Bin Abdulaziz University, Al-Kharj, Al Riyadh Province, Saudi Arabia.
J Multidiscip Healthc. 2021 May 12;14:1101-1106. doi: 10.2147/JMDH.S306703. eCollection 2021.
Patients' quality of life (QoL) and reported outcomes are critical indicators of the burden of a disease and the benefits of healthcare intervention. This systematic review explores publications that have adapted the EQ-5D for use with a population living in Saudi Arabia. The review of the following databases: MEDLINE, EMBASE, Wiley's Database, EBSCO, and ClinicalTrials.gov was conducted on December 1, 2020. The search strategy was adapted from the SPIDER search tool, and the included articles were classified by author, year of publication, region, disease of interest, sample size, type of EQ-5D, and format. Level of EQ-5D was classified as either 3L or 5L. Thirteen articles met the search inclusion criteria. The earliest publication was conducted in 2015 and the latest in 2020. These studies were conducted in four Saudi administrative regions, and multiple conditions or treatments were studied, the most studied condition being diabetes mellitus, followed by musculoskeletal disorders, back pain, and injuries. This systematic review article finds that the EQ-5D has been well adapted in the KSA. However, continued work is needed to investigate the quality of life for major conditions such as cardiovascular disease and cancer. Moreover, QoL research is lacking in certain regions, such as southern and northern Saudi Arabia. Despite the successful application and validation of the EQ-5D, a local QoL tool is needed to capture the unique context of patients within the healthcare system in the Middle East.
患者的生活质量（QoL）和报告的结果是疾病负担和医疗保健干预效益的关键指标。本系统评价探讨了对EQ-5D进行改编以用于沙特阿拉伯居民的相关出版物。于2020年12月1日对以下数据库进行了检索：MEDLINE、EMBASE、Wiley数据库、EBSCO和ClinicalTrials.gov。检索策略改编自SPIDER检索工具，纳入的文章按作者、发表年份、地区、感兴趣的疾病、样本量、EQ-5D的类型和格式进行分类。EQ-5D的版本分为3L或5L。13篇文章符合检索纳入标准。最早的出版物发表于2015年，最新的发表于2020年。这些研究在沙特的四个行政区进行，研究了多种疾病或治疗方法，研究最多的疾病是糖尿病，其次是肌肉骨骼疾病、背痛和损伤。本系统评价文章发现EQ-5D在沙特阿拉伯王国得到了很好的改编。然而，仍需要继续开展工作来调查心血管疾病和癌症等主要疾病的生活质量。此外，沙特阿拉伯南部和北部等某些地区缺乏生活质量研究。尽管EQ-5D已成功应用并得到验证，但仍需要一种本地生活质量工具来反映中东医疗保健系统中患者的独特情况。
