Alanazi Menyfah Q
Drug Policy and Economics Center, King Abdulaziz Medical City, Ministry of National Guard-Health Affairs, Riyadh, Saudi Arabia.
King Abdullah International Medical Research Center, Riyadh, Saudi Arabia.
Patient Prefer Adherence. 2020 Dec 4;14:2419-2426. doi: 10.2147/PPA.S277367. eCollection 2020.
Community-acquired urinary tract infection (CA-UTI) is a common and costly condition in females. Currently, there are no data on CA-UTI and quality of life (QoL) in Saudi Arabia. The aim of this study was to evaluate the impact of UTI and related socio-demographic characteristics on health-related quality of life (HRQoL) of Saudi females using the EuroQol 5-Dimension, 3-Level (EQ-5D-3L) instrument before and after treatment.
This was a cross-sectional questionnaire study conducted in the emergency department (ED) of a tertiary hospital over a three-month period.
A total of 339 out of 524 females with a mean age of 36.2 years (SD: 9.57 years; range 19-59 years) completed both the baseline and follow-up questionnaires of the EQ-5D-3L for a response rate of 64.7%. The baseline utility index for the worst health state "33333" was -0.495 representing 1.18% of the patients, and the full health state "11111" was 1 corresponding to 30.68% of the patients. The utility index after treatment for the moderate health state "22222" was 0.524 corresponding to 0.88% of the total patients, and the full health state "11111" was 1 corresponding to 80.24% of the patients. The mean EuroQol Visual Analogue Scale (EQ-VAS) was 73 ± 26 before treatment and 87.46 ± 18.55 after treatment. The frequency of patients reporting problems in the EQ-5D dimensions of mobility, self-care, usual activities, pain/discomfort and anxiety/depression decreased following treatment (27.43% vs 0.88%, 4.42% vs 0.88%, 25.96% vs 6.78%, 61.95% vs 13.27%, 39.52% vs 15.63%, respectively; all P < 0.001). There were statistically significant associations between HRQoL and socio-demographic characteristics, chronic diseases, and herbal supplements.
Community-acquired tract infections (CA-UTIs) have a significant negative impact on the HRQoL of Saudi females with a varying effect depending on the socio-demographic characteristics and chronic diseases.
社区获得性尿路感染（CA-UTI）在女性中是一种常见且代价高昂的疾病。目前，沙特阿拉伯尚无关于CA-UTI与生活质量（QoL）的数据。本研究的目的是使用欧洲五维度健康量表（EQ-5D-3L）评估尿路感染及相关社会人口学特征对沙特女性治疗前后健康相关生活质量（HRQoL）的影响。
这是一项在一家三级医院急诊科进行的为期三个月的横断面问卷调查研究。
524名平均年龄为36.2岁（标准差：9.57岁；范围19 - 59岁）的女性中，共有339名完成了EQ-5D-3L的基线和随访问卷，应答率为64.7%。最差健康状态“33333”的基线效用指数为 -0.495，占患者的1.18%，而完全健康状态“11111”为1，占患者的30.68%。治疗后中度健康状态“22222”的效用指数为0.524，占总患者的0.88%，完全健康状态“11111”为1，占患者的80.24%。治疗前欧洲五维度视觉模拟量表（EQ-VAS）的平均值为73 ± 26，治疗后为87.46 ± 18.55。治疗后，在EQ-5D的行动能力、自我护理、日常活动、疼痛/不适和焦虑/抑郁维度报告有问题的患者频率降低（分别为27.43%对0.88%、4.42%对0.88%、25.96%对6.78%、61.95%对13.27%、39.52%对15.63%；所有P < 0.001）。HRQoL与社会人口学特征、慢性病和草药补充剂之间存在统计学上的显著关联。
社区获得性尿路感染（CA-UTIs）对沙特女性的HRQoL有显著负面影响，其影响因社会人口学特征和慢性病而异。
