Paavonen T, Aronen H, Saarelainen I, Neittaanmäki H, Hjelm I, Kiistala U
Department of Pathology, University of Helsinki, Finland.
Br J Dermatol. 1988 Jun;118(6):753-7. doi: 10.1111/j.1365-2133.1988.tb02592.x.
We measured levels of creatine kinase and its three isoenzymes in serum and blister fluid from 16 healthy volunteers. The BB-isoenzyme was found to be the predominant form in blister fluid while only the MM isoenzyme was found in serum. The levels of BB-isoenzyme in blister fluid decreased as the blisters aged. The source of BB-isoenzyme in blister fluid is most probably the damaged epidermis.