Clinton Health Access Initiative, Boston, Massachusetts, USA.
Coalition for Global Hepatitis Elimination, Task Force for Global Health, Decatur, Georgia, USA.
Clin Infect Dis. 2022 Feb 11;74(3):513-516. doi: 10.1093/cid/ciab461.
Access to recommended second-line treatments is limited for patients who fail initial hepatitis C virus (HCV) therapy in low- and middle-income countries. Alternative regimens and associated outcomes are not well understood. Through a pooled analysis of national program data in Egypt, Georgia, and Myanmar, we observed SVR rates >90% for alternative retreatment regimens.
在中低收入国家,对于初始丙型肝炎病毒(HCV)治疗失败的患者,推荐的二线治疗方法有限。替代方案及其相关结果尚不清楚。通过对埃及、格鲁吉亚和缅甸国家项目数据的汇总分析,我们观察到替代再治疗方案的 SVR 率>90%。