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经导管主动脉瓣置换术治疗髋部骨折合并严重主动脉瓣狭窄患者:如何进行及何时进行?

TAVR in patients with hip fracture and severe aortic stenosis: how and when?

机构信息

Dipartimento Medicina Sperimentale e Clinica, Università di Firenze, Viale Morgagni 85, 50134, Florence, Italy.

Cardiologia Interventistica AOU Careggi, 50134, Florence, Italy.

出版信息

Intern Emerg Med. 2021 Sep;16(6):1419-1422. doi: 10.1007/s11739-021-02752-6. Epub 2021 May 20.

Abstract

Comorbidities are common in elderly patients with hip fracture and are associated with an increased mortality after surgery. Internal medicine/geriatric leaded multidisciplinary hip fracture teams may play a pivotal role in the clinical management of complex patients. Treatment strategy is particular relevant in patients with severe aortic stenosis that represent more than 5% of patients with hip fracture. These patients have a high in-hospital mortality and poor 1-year survival (less than 50%). Transcatheter aortic valve replacement (TAVR) may be an option in selected patients; however, the choice to treat and, in the case, the timing of valve replacement in relation to hip surgery is highly dependent on clinical conditions before trauma. In this paper, three different scenario of TAVR timing after hip fracture are reported.

摘要

合并症在老年髋部骨折患者中很常见,并且与手术后死亡率增加有关。内科/老年多学科髋部骨折团队可能在复杂患者的临床管理中发挥关键作用。对于主动脉瓣狭窄严重的患者(超过髋部骨折患者的 5%),治疗策略特别重要。这些患者的院内死亡率高,1 年生存率低(<50%)。经导管主动脉瓣置换术(TAVR)可能是某些患者的选择;然而,是否进行治疗以及在何种情况下进行瓣膜置换与髋部手术的时机高度取决于创伤前的临床状况。本文报告了髋部骨折后 TAVR 时机的三种不同情况。

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